This software is under this license: =========================================================== Copyright (C) 2007 Piero Fariselli This program is free software: you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation, either version 3 of the License, or (at your option) any later version. This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. You should have received a copy of the GNU General Public License along with this program. If not, see . PHMM lib Copyright (C) 2007 Piero Fariselli contacts: Piero Fariselli e-mail: piero@biocomp.unibo.it, piero.fariselli@unibo.it Dept. of Biology University of Bologna via Irnerio 42 40126 Bologna Italy This program comes with ABSOLUTELY NO WARRANTY; for details type psCoils.py. This is free software, and you are welcome to redistribute it under the condition of preserving this text =========================================================== #--------------------------------------------------------------------------------# # REQUIREMENTS # #--------------------------------------------------------------------------------# # # # !!!!!!! You need python2.x installed and the numpy package. !!!!!!! # # # #--------------------------------------------------------------------------------# TO RUN just type: $ pred.py file.in where file.in must contains the protein sequence in the form of protein profile. Each line is one sequence position and the order of the profile is: # the order of the 20 symbol is : V L I M F W Y G A P S T C H R K Q E N D The output consits of two lines: the first line assign probability to contain a coiled-coil segment. The second line assign a putative prediction in which the symbol 'H' represent possible coiled-coil positions. However, the probability must be also taken into account. Please for any use of this software cite the paper: Bartoli L, Fariselli P, Krogh A, Casadio R (2009) -CCHMM_PROF: a HMM-based coiled-coil predictor with evolutionary information- Bioinformatics 25:2757-2763 (2009)