# PDB => the pdb code # Mut => the mutation carried out # %ASA => relative accessibility # T => experimental temperature # PH => experimental PH # ddg => experimental free energy stability variation # S_ddG => FOLD-X predicted value # NNSer => I-Mutant server prediction # RI => I-Mutant server reliability # NNPr => I-Mutant cross-validation prediction # RI2 => I-Mutant cross-validation reliability # SP => FOLD-X ddG-sign correctness # NNP => I-Mutant cross-validation ddG-sign correctness # NNSER => I-Mutant server ddG-sign correctness # # # PDB Mut %ASA T PH ddG S_ddG NNSer RI NNPr RI2 SP NNP NNSER 2RN2 D134N 37.50 50.00 3.00 0.10 1.66 Increase 5 Increase 8 YES NO NO 2RN2 D134N 37.50 53.00 5.50 -0.89 1.66 Increase 6 Increase 2 NO YES YES 1BNI D93N 48.60 25.00 6.30 4.11 -0.04 Decrease 0 Increase 4 NO NO YES 2LZM D20N 38.90 65.00 5.40 -1.30 -1.93 Increase 8 Increase 8 YES YES YES 1BNI D54N 22.20 25.00 4.40 2.65 -0.07 Decrease 8 Decrease 8 NO YES YES 1BNI D54N 22.20 25.00 6.30 2.40 -0.07 Decrease 7 Decrease 7 NO YES YES 1BNI D54N 22.20 25.00 8.90 2.32 -0.07 Decrease 7 Decrease 8 NO YES YES 1ROP D30N 96.50 69.00 7.00 -0.80 -0.11 Decrease 0 Decrease 1 YES NO NO 6ICB D19N 50.70 25.00 7.00 -0.74 -0.84 Decrease 4 Decrease 7 YES NO NO 4LYZ D101N 72.20 74.00 6.40 -0.04 -1.01 Increase 8 Increase 8 YES YES YES 1BNI D75N 0.00 25.00 6.30 4.80 0.92 Decrease 9 Decrease 9 YES YES YES 2RN2 D70N 40.20 47.00 9.00 -1.60 -0.28 Increase 2 Increase 2 YES YES YES 2RN2 D70N 40.20 50.00 3.00 0.30 -0.28 Increase 1 Increase 7 NO NO NO 3MBP D55N 42.30 25.00 7.60 -0.00 -0.51 Decrease 5 Decrease 7 NO NO NO 2LZM D92N 38.90 39.00 2.00 0.10 0.97 Decrease 7 Decrease 7 YES YES YES 2LZM D92N 38.90 62.00 6.70 1.40 0.97 Decrease 5 Decrease 5 YES YES YES 2RN2 D10N 9.70 47.00 9.00 -2.00 -0.75 Increase 2 Increase 3 YES YES YES 2RN2 D10N 9.70 50.00 3.00 0.70 -0.75 Increase 1 Increase 4 NO NO NO 1RN1 D76N 1.40 15.00 7.00 3.10 -1.30 Decrease 9 Decrease 9 NO YES YES 1VQB D36N 47.20 25.00 7.00 1.00 0.43 Decrease 8 Decrease 9 YES YES YES 1RTB D121N 8.30 25.00 1.20 0.76 1.57 Decrease 9 Decrease 9 YES YES YES 1RTB D121N 8.30 25.00 6.00 1.90 1.57 Decrease 9 Decrease 9 YES YES YES 2LZM N163D 89.50 65.00 5.40 0.21 0.26 Increase 9 Increase 9 YES NO NO 1BNI N58D 16.40 25.00 6.30 -0.50 1.33 Decrease 5 Decrease 8 NO NO NO 2LZM N40D 84.70 65.00 5.40 -0.44 -0.27 Increase 9 Increase 9 YES YES YES 2LZM N144D 75.80 40.00 2.00 0.10 -0.38 Increase 1 Increase 3 NO NO NO 2LZM N144D 75.80 53.00 3.00 -0.40 -0.38 Increase 6 Increase 5 YES YES YES 2LZM N144D 75.80 66.00 5.40 -0.41 -0.38 Increase 9 Increase 8 YES YES YES 2LZM N144D 75.80 66.00 6.90 -0.50 -0.38 Increase 9 Increase 9 YES YES YES 2AKY N169D 43.00 25.00 7.50 2.15 4.00 Decrease 8 Decrease 7 YES YES YES 1RN1 N44D 18.40 50.00 7.00 1.60 3.17 Decrease 6 Decrease 5 YES YES YES 4LYZ N103D 54.00 20.00 9.50 -0.24 0.02 Increase 3 Increase 5 NO YES YES 1BNI N41D 19.80 25.00 6.30 2.50 2.52 Decrease 6 Decrease 3 YES YES YES 2LZM N116D 58.70 40.00 2.00 0.10 -0.72 Increase 1 Increase 5 NO NO NO 2LZM N116D 58.70 53.00 3.00 -0.34 -0.72 Increase 6 Increase 8 YES YES YES 2LZM N116D 58.70 66.00 5.70 -0.60 -0.72 Increase 9 Increase 9 YES YES YES 2LZM N116D 58.70 66.00 5.70 -0.60 -0.72 Increase 9 Increase 9 YES YES YES 1SAR N39D 11.60 48.00 7.00 1.50 1.64 Decrease 8 Decrease 8 YES YES YES 1SUP N76D 69.70 58.00 8.00 -0.45 -0.39 Increase 7 Increase 9 YES YES YES 1STN N118D 6.10 20.00 7.00 2.50 3.11 Decrease 9 Decrease 9 YES YES YES 2CI2 N75D 32.80 25.00 6.20 1.21 0.89 Decrease 7 Decrease 4 YES YES YES 2RN2 D134E 37.50 50.00 3.00 -0.72 0.11 Increase 8 Increase 7 NO YES YES 2RN2 D134E 37.50 53.00 5.50 -0.86 0.11 Increase 8 Increase 9 NO YES YES 1ROP D30E 96.50 69.00 7.00 -1.00 0.06 Increase 1 Decrease 0 NO NO YES 4LYZ D101E 72.20 74.00 6.40 -0.00 0.43 Increase 9 Increase 10 NO NO NO 2RN2 D94E 76.30 49.00 3.00 0.40 0.70 Increase 0 Increase 1 YES NO NO 2RN2 D94E 76.30 49.00 3.00 0.40 0.70 Increase 0 Increase 1 YES NO NO 2RN2 D70E 40.20 47.00 9.00 -0.10 1.43 Increase 5 Increase 4 NO YES YES 2RN2 D70E 40.20 50.00 3.00 -0.50 1.43 Increase 5 Increase 5 NO YES YES 1BNI D44E 90.90 25.00 6.30 -0.10 -0.50 Increase 5 Increase 1 YES YES YES 2RN2 D10E 9.70 47.00 9.00 -1.00 1.36 Increase 7 Increase 8 NO YES YES 2RN2 D10E 9.70 50.00 3.00 -1.10 1.36 Increase 6 Increase 6 NO YES YES 2LZM N144E 75.80 40.00 2.00 -0.20 -0.51 Decrease 0 Decrease 1 YES NO NO 2LZM N144E 75.80 66.00 5.50 -0.50 -0.51 Increase 8 Increase 7 YES YES YES 2LZM N144E 75.80 66.00 5.50 -0.50 -0.51 Increase 8 Increase 7 YES YES YES 2RN2 E48D 12.00 47.00 9.00 0.20 4.25 Decrease 3 Decrease 0 YES YES YES 2RN2 E48D 12.00 50.00 3.00 -0.20 4.25 Decrease 4 Decrease 7 NO NO NO 2CI2 E34D 60.10 25.00 6.20 0.74 -0.12 Decrease 8 Decrease 7 NO YES YES 2CI2 E33D 57.20 25.00 6.20 0.52 -0.82 Decrease 8 Decrease 9 NO YES YES 1VQB E30N 28.60 25.00 7.00 1.10 0.42 Decrease 9 Decrease 9 YES YES YES 2LZM E11N 21.20 65.00 5.40 0.10 -0.52 Decrease 2 Decrease 2 NO YES YES 2CI2 E34N 60.10 25.00 6.20 1.07 -0.09 Decrease 7 Decrease 7 NO YES YES 2CI2 E33N 57.20 25.00 6.20 0.70 -0.48 Decrease 8 Decrease 8 NO YES YES 2CI2 E33N 57.20 25.00 6.20 0.70 -0.48 Decrease 8 Decrease 8 NO YES YES 2RN2 D134Q 37.50 50.00 3.00 -0.48 -0.44 Increase 9 Increase 9 YES YES YES 2RN2 D134Q 37.50 53.00 5.50 -1.32 -0.44 Increase 9 Increase 10 YES YES YES 1ROP D30Q 96.50 69.00 7.00 -1.80 -0.34 Increase 6 Increase 3 YES YES YES 4LYZ D101Q 72.20 74.00 6.40 0.08 -1.10 Increase 9 Increase 10 NO NO NO 6ICB E17Q 62.40 25.00 7.00 -0.38 -1.06 Increase 3 Decrease 2 YES NO YES 1DDR E139Q 47.50 15.00 7.80 1.36 0.41 Decrease 5 Decrease 6 YES YES YES 1BNI E29Q 55.00 25.00 6.30 -0.00 -0.09 Decrease 2 Decrease 6 NO NO NO 6ICB E26Q 81.30 25.00 7.00 -0.09 -0.31 Decrease 5 Decrease 9 YES NO NO 2RN2 E48Q 12.00 47.00 9.00 -0.30 0.36 Decrease 3 Decrease 6 NO NO NO 2RN2 E48Q 12.00 50.00 3.00 0.10 0.36 Decrease 4 Decrease 5 YES YES YES 2CI2 E26Q 52.10 25.00 6.20 0.62 -0.62 Decrease 6 Decrease 5 NO YES YES 2CI2 E34Q 60.10 25.00 6.20 0.47 -0.28 Decrease 8 Decrease 8 NO YES YES 2CI2 E33Q 57.20 25.00 6.20 0.29 -0.09 Decrease 9 Decrease 8 NO YES YES 2LZM Q123E 56.00 40.00 2.00 -0.30 -0.72 Decrease 2 Decrease 5 YES NO NO 2LZM Q123E 56.00 64.00 6.50 -0.40 -0.72 Increase 3 Decrease 0 YES NO YES 2LZM Q123E 56.00 66.00 5.50 -0.10 -0.72 Increase 3 Increase 1 YES YES YES 1C9O Q53E 100.80 70.00 7.00 0.10 0.01 Increase 3 Decrease 0 YES YES NO 1C9O Q53E 100.80 70.00 7.00 -0.00 0.01 Increase 3 Decrease 0 NO NO NO 2LZM Q105E 31.90 42.00 2.10 0.50 1.02 Decrease 7 Decrease 6 YES YES YES 2LZM Q105E 31.90 66.00 5.80 1.10 1.02 Decrease 3 Decrease 1 YES YES YES 1ROP D30K 96.50 69.00 7.00 -0.90 -0.06 Increase 2 Increase 0 YES YES YES 4LYZ D101K 72.20 74.00 6.40 -0.19 -0.09 Increase 8 Increase 7 YES YES YES 4LYZ N19K 68.30 74.00 6.40 1.06 -0.64 Increase 5 Increase 9 NO NO NO 2LZM E22K 50.40 65.00 5.40 -0.57 0.20 Increase 1 Decrease 8 NO NO YES 2RN2 E135K 70.40 50.00 3.00 1.10 -0.37 Increase 6 Increase 9 NO NO NO 2RN2 E135K 70.40 52.00 5.50 0.22 -0.37 Increase 7 Increase 10 NO NO NO 1DDR E139K 47.50 15.00 7.80 2.36 -1.21 Decrease 7 Decrease 6 NO YES YES 2LZM E128K 55.50 47.00 3.00 1.16 -0.37 Decrease 5 Decrease 4 NO YES YES 1RN1 Q25K 48.70 48.00 7.00 -0.93 -0.13 Increase 6 Increase 8 YES YES YES 4LYZ K13D 36.50 20.00 9.50 6.70 1.67 Decrease 6 Decrease 7 YES YES YES 1C2R K12D 37.40 25.00 7.50 1.30 0.50 Decrease 6 Decrease 7 YES YES YES 2RN2 K95N 68.10 49.00 3.00 -0.90 0.29 Decrease 0 Decrease 2 NO NO NO 2RN2 K95N 68.10 49.00 3.00 -0.90 0.29 Decrease 0 Decrease 2 NO NO NO 2RN2 K95N 68.10 52.00 5.50 -0.88 0.29 Increase 1 Increase 1 NO YES YES 2RN2 K95N 68.10 52.00 5.50 -0.88 0.29 Increase 1 Increase 1 NO YES YES 2CI2 K72N 102.60 25.00 6.20 -0.00 0.35 Decrease 3 Decrease 2 NO NO NO 1AAR K29N 22.40 25.00 5.00 1.48 0.62 Decrease 6 Decrease 2 YES YES YES 1C2R K32E 67.60 25.00 7.50 -0.20 -3.10 Increase 1 Increase 3 YES YES YES 2LZM K135E 71.50 50.00 2.80 0.20 0.30 Increase 5 Increase 10 YES NO NO 2LZM K135E 71.50 66.00 5.30 1.00 0.30 Increase 7 Increase 10 YES NO NO 2LZM K147E 41.80 50.00 2.80 -0.10 -1.78 Increase 1 Increase 0 YES YES YES 2LZM K147E 41.80 66.00 5.30 0.70 -1.78 Increase 5 Increase 9 NO NO NO 2LZM K16E 58.80 50.00 2.80 0.50 0.23 Decrease 4 Decrease 1 YES YES YES 2LZM K16E 58.80 66.00 5.30 -0.50 0.23 Increase 0 Decrease 2 NO NO YES 1C2R K14E 51.50 25.00 7.50 1.30 1.95 Decrease 5 Decrease 7 YES YES YES 2ABD K32E 28.20 5.00 5.30 1.68 1.47 Decrease 2 Decrease 4 YES YES YES 1POH K49E 44.70 30.00 7.00 -1.90 -1.21 Decrease 4 Decrease 5 YES NO NO 1POH K49E 44.70 63.00 7.00 -2.10 -1.21 Increase 2 Decrease 0 YES NO YES 1AAR K6E 29.20 25.00 5.00 -0.53 -0.25 Decrease 6 Decrease 6 YES NO NO 1AAR K6Q 29.20 25.00 5.00 -0.26 -0.96 Decrease 6 Decrease 6 YES NO NO 1AAR K29Q 22.40 25.00 5.00 1.67 0.20 Decrease 7 Decrease 8 YES YES YES 1AAR K27Q 5.30 25.00 5.00 1.91 3.80 Decrease 8 Decrease 9 YES YES YES 1ROP D30R 96.50 69.00 7.00 -0.80 -0.10 Increase 6 Increase 4 YES YES YES 4LYZ D101R 72.20 74.00 6.40 -0.27 -0.05 Increase 10 Increase 10 YES YES YES 1CSP E3R 42.40 70.00 7.00 -2.66 -2.80 Increase 4 Increase 1 YES YES YES 1BNI K62R 41.30 25.00 6.30 0.40 -0.26 Increase 6 Increase 7 NO NO NO 1BNI K108R 52.50 25.00 6.30 -0.90 -0.57 Increase 2 Decrease 1 YES NO YES 1BNI K19R 30.10 25.00 6.30 -0.20 -0.61 Decrease 4 Decrease 6 YES NO NO 2ABD K32R 28.20 5.00 5.30 1.83 2.61 Increase 2 Increase 1 YES NO NO 2RN2 K117R 54.90 50.00 3.00 0.06 0.00 Decrease 0 Increase 2 NO NO YES 2RN2 K117R 54.90 52.00 5.50 -0.03 0.00 Decrease 0 Decrease 0 NO NO NO 2RN2 K91R 42.80 49.00 3.00 -0.20 0.53 Increase 8 Increase 7 NO YES YES 2RN2 K91R 42.80 49.00 5.50 -0.00 0.53 Increase 8 Increase 8 NO NO NO 1IOB K97R 41.30 25.00 6.50 0.50 -3.79 Decrease 5 Decrease 8 NO YES YES 2LZM R119E 49.80 50.00 2.80 0.20 -1.11 Decrease 5 Decrease 4 NO YES YES 2LZM R119E 49.80 66.00 5.30 0.04 -1.11 Decrease 0 Decrease 0 NO YES YES 2LZM R154E 36.70 50.00 2.80 -0.20 1.87 Decrease 6 Decrease 9 NO NO NO 2LZM R154E 36.70 66.00 5.30 1.10 1.87 Decrease 5 Decrease 4 YES YES YES 1AAR R42E 28.40 25.00 5.00 -1.63 -0.61 Decrease 8 Decrease 8 YES NO NO 1C9O R3E 71.60 70.00 7.00 2.75 2.39 Decrease 3 Decrease 3 YES YES YES 4LYZ R21Q 68.10 74.00 6.40 0.15 1.14 Increase 7 Increase 9 YES NO NO 1BNI R83Q 29.70 25.00 4.40 1.58 -0.64 Decrease 6 Decrease 5 NO YES YES 1BNI R83Q 29.70 25.00 6.30 2.05 -0.64 Decrease 6 Decrease 5 NO YES YES 1AAR R72Q 59.80 25.00 5.00 0.33 -0.10 Decrease 8 Decrease 9 NO YES YES 1TUP R248Q 73.80 10.00 7.20 1.94 0.24 Decrease 5 Increase 4 YES NO YES 4LYZ R68K 52.00 74.00 6.40 0.04 -0.39 Decrease 4 Decrease 0 NO YES YES 4LYZ R73K 68.60 74.00 6.40 -0.23 -0.91 Decrease 0 Decrease 6 YES NO NO 1BNI R69K 16.60 25.00 6.30 3.13 -0.16 Decrease 9 Decrease 9 NO YES YES 1BNI R83K 29.70 25.00 6.30 4.13 0.86 Decrease 8 Decrease 8 YES YES YES 2LZM R14K 55.00 65.00 5.40 0.03 -1.05 Decrease 3 Decrease 8 NO YES YES 2LZM R80K 80.30 65.00 5.40 0.17 0.43 Decrease 5 Decrease 8 YES YES YES 1C9O R3K 71.60 70.00 7.00 0.19 -0.24 Decrease 5 Decrease 5 NO YES YES 2RN2 D134H 37.50 50.00 3.00 -0.50 0.31 Increase 6 Increase 5 NO YES YES 2RN2 D134H 37.50 52.00 5.50 -1.90 0.31 Increase 7 Increase 8 NO YES YES 2RN2 D134H 37.50 53.00 5.50 -1.94 0.31 Increase 7 Increase 5 NO YES YES 2ABD D21H 22.20 5.00 5.30 0.56 -0.09 Decrease 9 Decrease 9 NO YES YES 1ROP D30H 96.50 69.00 7.00 -0.90 -0.05 Decrease 0 Decrease 1 YES NO NO 1VQB D50H 34.00 25.00 7.00 1.50 1.14 Decrease 7 Decrease 7 YES YES YES 2RN2 D10H 9.70 47.00 9.00 -2.40 -3.09 Increase 3 Increase 0 YES YES YES 2RN2 D10H 9.70 50.00 3.00 -0.40 -3.09 Increase 2 Increase 1 YES YES YES 1ANK D84H 9.00 51.00 7.20 1.40 0.50 Decrease 6 Decrease 5 YES YES YES 4LYZ N77H 92.90 74.00 6.40 0.38 0.22 Increase 3 Increase 7 YES NO NO 2LZM N144H 75.80 39.00 2.00 0.60 0.90 Decrease 4 Decrease 5 YES YES YES 2LZM N144H 75.80 62.00 6.70 -0.30 0.90 Increase 5 Increase 3 NO YES YES 2LZM E11H 21.20 65.00 5.40 -0.10 -1.15 Decrease 2 Decrease 6 YES NO NO 4LYZ Q121H 69.40 74.00 6.40 0.45 0.28 Decrease 6 Decrease 7 YES YES YES 1VQB K69H 51.00 25.00 7.00 1.20 1.05 Decrease 4 Decrease 7 YES YES YES 2LZM K60H 51.00 28.00 2.00 0.80 0.45 Decrease 7 Decrease 6 YES YES YES 2LZM K60H 51.00 63.00 6.50 0.10 0.45 Decrease 1 Increase 1 YES NO YES 2LZM K83H 67.60 28.00 2.00 0.50 -0.97 Decrease 5 Decrease 8 NO YES YES 2LZM K83H 67.60 63.00 6.50 0.40 -0.97 Decrease 1 Increase 0 NO NO YES 4LYZ R114H 62.40 74.00 6.40 -0.68 0.22 Increase 7 Decrease 3 NO NO YES 1TUP R175H 1.30 10.00 7.20 3.01 -0.49 Decrease 8 Decrease 8 NO YES YES 1TUP R273H 27.90 10.00 7.20 0.35 0.42 Decrease 9 Decrease 9 YES YES YES 2LZM R119H 49.80 65.00 5.40 0.29 -0.48 Decrease 3 Decrease 6 NO YES YES 2LZM R96H 33.60 65.00 6.00 2.82 -1.04 Decrease 7 Decrease 7 NO YES YES 2LZM R96H 33.60 70.00 6.50 2.80 -1.04 Decrease 7 Decrease 5 NO YES YES 1BNI H18D 59.40 25.00 6.30 2.56 1.04 Decrease 7 Decrease 8 YES YES YES 2RN2 H62D 73.70 50.00 3.00 -0.67 -1.06 Decrease 2 Decrease 5 YES NO NO 2RN2 H62D 73.70 52.00 5.50 0.17 -1.06 Decrease 1 Decrease 1 NO YES YES 1BNI H18N 59.40 25.00 6.30 1.68 -0.46 Decrease 7 Decrease 5 NO YES YES 2LZM H31N 17.60 66.00 5.50 4.00 -0.85 Decrease 3 Decrease 2 NO YES YES 1AAR H68E 37.40 25.00 5.00 -0.77 0.28 Decrease 9 Decrease 9 NO NO NO 1BVC H36Q 23.60 4.00 7.80 0.80 -0.40 Decrease 6 Decrease 3 NO YES YES 1BNI H18Q 59.40 25.00 6.30 1.60 -0.37 Decrease 7 Decrease 7 NO YES YES 1AAR H68Q 37.40 25.00 5.00 -0.55 0.57 Decrease 8 Decrease 9 NO NO NO 1BNI H18K 59.40 25.00 6.30 1.20 -0.54 Decrease 8 Decrease 9 NO YES YES 1BNI H18R 59.40 25.00 6.30 1.17 -1.13 Decrease 6 Decrease 8 NO YES YES 2RN2 H62R 73.70 50.00 3.00 0.03 -0.49 Increase 0 Decrease 0 NO YES NO 2RN2 H62R 73.70 52.00 5.50 -0.36 -0.49 Increase 1 Increase 1 YES YES YES 1ROP D30C 96.50 69.00 7.00 -0.80 -0.12 Increase 7 Increase 9 YES YES YES 1VQB D36C 47.20 25.00 7.00 2.00 0.36 Decrease 8 Decrease 9 YES YES YES 1VQB E40C 107.00 25.00 7.00 1.60 0.04 Decrease 3 Decrease 1 YES YES YES 1SUP Q206C 40.90 58.00 8.00 -1.25 -0.63 Increase 1 Decrease 6 YES NO YES 2RN2 R41C 54.10 50.00 3.00 -0.12 0.51 Increase 7 Increase 1 NO YES YES 2RN2 R41C 54.10 52.00 5.50 -0.44 0.51 Increase 8 Increase 8 NO YES YES 1VQB R82C 18.30 25.00 7.00 1.50 -0.22 Decrease 9 Decrease 6 NO YES YES 1VQB H64C 48.40 25.00 7.00 -0.50 -0.45 Decrease 7 Decrease 8 YES NO NO 2RN2 D134T 37.50 50.00 3.00 -0.12 -0.62 Increase 9 Increase 10 YES YES YES 2RN2 D134T 37.50 53.00 5.50 -1.08 -0.62 Increase 9 Increase 9 YES YES YES 2LZM D20T 38.90 65.00 5.40 -0.90 -1.97 Increase 8 Increase 6 YES YES YES 1ROP D30T 96.50 69.00 7.00 0.40 -0.14 Increase 9 Increase 9 NO NO NO 1VQB E40T 107.00 25.00 7.00 0.40 0.08 Decrease 4 Decrease 6 YES YES YES 1RN1 H40T 33.00 25.00 6.00 0.26 0.38 Decrease 6 Decrease 4 YES YES YES 2LZM C54T 3.60 65.00 6.00 -1.36 -1.96 Decrease 3 Decrease 9 YES NO NO 2LZM C54T 3.60 70.00 6.50 -0.30 -1.96 Decrease 1 Decrease 9 YES NO NO 1VQB C33T 0.00 25.00 7.00 4.60 0.29 Decrease 9 Decrease 9 YES YES YES 1BNI T26D 23.10 25.00 6.30 0.08 4.24 Decrease 7 Decrease 9 YES YES YES 2CI2 T58D 75.00 25.00 6.30 -0.04 0.57 Decrease 4 Decrease 3 NO NO NO 2LZM T59D 46.90 41.00 2.00 0.90 1.06 Decrease 7 Decrease 5 YES YES YES 2LZM T59D 46.90 63.00 6.50 1.20 1.06 Decrease 5 Decrease 4 YES YES YES 2LZM T157D 35.30 42.00 2.00 1.10 1.87 Decrease 6 Decrease 5 YES YES YES 2LZM T109D 82.20 39.00 2.00 0.30 -0.64 Increase 2 Increase 6 NO NO NO 2LZM T109D 82.20 62.00 6.70 -0.60 -0.64 Increase 7 Increase 3 YES YES YES 1BNI T6D 49.00 25.00 6.30 -0.11 0.70 Decrease 8 Decrease 9 NO NO NO 1BNI T26N 23.10 25.00 6.30 1.29 0.59 Decrease 7 Decrease 7 YES YES YES 2LZM T59N 46.90 41.00 2.00 0.60 0.01 Decrease 7 Decrease 6 YES YES YES 2LZM T59N 46.90 63.00 6.50 1.10 0.01 Decrease 5 Decrease 4 YES YES YES 2LZM T157N 35.30 38.00 2.00 1.00 1.75 Decrease 6 Decrease 3 YES YES YES 2LZM T157N 35.30 42.00 2.00 0.45 1.75 Decrease 6 Decrease 8 YES YES YES 2LZM T157N 35.30 46.00 2.50 1.10 1.75 Decrease 6 Decrease 5 YES YES YES 2LZM T157N 35.30 53.00 3.00 1.20 1.75 Decrease 5 Decrease 5 YES YES YES 2LZM T109N 82.20 39.00 2.00 -0.00 0.11 Decrease 1 Decrease 1 NO NO NO 2LZM T109N 82.20 62.00 6.70 -0.10 0.11 Increase 3 Increase 8 NO YES YES 1BNI T6N 49.00 25.00 6.30 1.27 0.17 Decrease 8 Decrease 7 YES YES YES 1BNI T26E 23.10 25.00 6.30 0.05 3.70 Decrease 7 Decrease 6 YES YES YES 2LZM T157E 35.30 42.00 2.00 1.50 1.80 Decrease 6 Decrease 7 YES YES YES 2LZM T157E 35.30 42.00 2.00 1.50 1.80 Decrease 6 Decrease 7 YES YES YES 2LZM T157E 35.30 46.00 2.50 1.30 1.80 Decrease 6 Decrease 4 YES YES YES 2LZM T157E 35.30 53.00 3.00 0.80 1.80 Decrease 5 Decrease 5 YES YES YES 1BNI T6E 49.00 25.00 6.30 0.27 0.57 Decrease 8 Decrease 7 YES YES YES 2LZM T115E 63.40 40.00 2.00 0.50 -0.40 Decrease 5 Decrease 4 NO YES YES 2LZM T115E 63.40 52.00 3.00 0.20 -0.40 Decrease 2 Decrease 2 NO YES YES 2LZM T115E 63.40 63.00 4.00 0.10 -0.40 Decrease 0 Increase 1 NO NO YES 2LZM T115E 63.40 66.00 6.50 -0.30 -0.40 Increase 1 Decrease 0 YES NO YES 2LZM T115E 63.40 66.00 5.50 -0.00 -0.40 Increase 1 Decrease 1 NO NO NO 2LZM T115E 63.40 66.00 6.50 -0.30 -0.40 Increase 1 Decrease 0 YES NO YES 1BNI T26Q 23.10 25.00 6.30 1.72 2.57 Decrease 7 Decrease 5 YES YES YES 1BNI T6Q 49.00 25.00 6.30 1.87 -1.02 Decrease 8 Decrease 8 NO YES YES 1IOB T9Q 4.30 25.00 6.50 1.90 -0.27 Decrease 9 Decrease 9 NO YES YES 1BNI T16R 72.10 25.00 4.40 -0.20 0.65 Decrease 4 Decrease 6 NO NO NO 1BNI T16R 72.10 25.00 6.30 0.48 0.65 Decrease 4 Decrease 4 YES YES YES 1BNI T16R 72.10 25.00 6.30 -0.50 0.65 Decrease 4 Decrease 8 NO NO NO 2LZM T157R 35.30 38.00 2.00 1.10 1.60 Decrease 6 Decrease 4 YES YES YES 2LZM T157R 35.30 42.00 2.00 1.30 1.60 Decrease 5 Decrease 3 YES YES YES 2LZM T157R 35.30 46.00 2.50 0.60 1.60 Decrease 4 Decrease 3 YES YES YES 2LZM T157R 35.30 53.00 3.00 -0.30 1.60 Decrease 3 Decrease 4 NO NO NO 2AKY T77H 74.30 25.00 7.50 2.15 -0.68 Decrease 5 Decrease 4 NO YES YES 2LZM T157H 35.30 42.00 2.00 2.10 1.70 Decrease 7 Decrease 4 YES YES YES 1BNI T6H 49.00 25.00 4.40 2.65 -0.14 Decrease 8 Decrease 9 NO YES YES 1BNI T6H 49.00 25.00 8.90 1.56 -0.14 Decrease 8 Decrease 7 NO YES YES 1VQB T48C 25.20 25.00 7.00 0.80 0.09 Decrease 7 Decrease 9 YES YES YES 2LZM T157C 35.30 42.00 2.00 1.30 1.77 Decrease 5 Decrease 3 YES YES YES 2LZM T152C 0.00 59.00 5.40 0.50 0.71 Decrease 4 Decrease 1 YES YES YES 1VQB T62C 14.40 25.00 7.00 0.70 1.22 Decrease 6 Decrease 6 YES YES YES 2RN2 D134S 37.50 50.00 3.00 -0.26 -0.72 Increase 9 Increase 8 YES YES YES 2RN2 D134S 37.50 53.00 5.50 -1.08 -0.72 Increase 9 Increase 9 YES YES YES 2LZM D20S 38.90 65.00 5.40 -0.70 -1.38 Increase 8 Increase 6 YES YES YES 1ROP D30S 96.50 69.00 7.00 -1.00 -0.07 Increase 4 Increase 6 YES YES YES 4LYZ D101S 72.20 74.00 6.40 -0.87 -2.08 Increase 9 Increase 8 YES YES YES 1BNI D8S 65.20 25.00 6.30 0.97 0.35 Decrease 8 Decrease 9 YES YES YES 1BNI D12S 59.70 25.00 6.30 0.65 0.67 Decrease 7 Decrease 8 YES YES YES 2RN2 D10S 9.70 47.00 9.00 -2.70 0.06 Increase 3 Increase 4 NO YES YES 2RN2 D10S 9.70 50.00 3.00 -0.70 0.06 Increase 1 Decrease 2 NO NO YES 1RN1 D76S 1.40 15.00 7.00 3.30 -1.21 Decrease 9 Decrease 9 NO YES YES 1C9O N11S 53.30 70.00 7.00 -0.33 -0.22 Increase 9 Increase 7 YES YES YES 1RN1 N44S 18.40 50.00 7.00 1.50 1.64 Decrease 7 Decrease 4 YES YES YES 1SUP N218S 66.30 58.00 8.00 -1.07 0.14 Increase 10 Increase 10 NO YES YES 1SAR N39S 11.60 48.00 7.00 2.30 0.45 Decrease 9 Decrease 9 YES YES YES 1BNI E29S 55.00 25.00 6.30 1.23 1.37 Decrease 6 Decrease 7 YES YES YES 1BNI Q31S 65.50 25.00 6.30 0.20 1.28 Decrease 6 Decrease 5 YES YES YES 1BNI R69S 16.60 25.00 6.30 2.72 0.41 Decrease 9 Decrease 9 YES YES YES 1TUP R249S 14.00 10.00 7.20 1.95 1.34 Decrease 9 Decrease 9 YES YES YES 1BNI H18S 59.40 25.00 6.30 2.28 0.97 Decrease 8 Decrease 9 YES YES YES 1TUP C242S 12.10 10.00 7.20 2.94 -1.28 Decrease 9 Decrease 9 NO YES YES 1VQB C33S 0.00 25.00 7.00 4.20 1.57 Decrease 9 Decrease 9 YES YES YES 1BNI T26S 23.10 25.00 6.30 0.56 0.20 Decrease 8 Decrease 8 YES YES YES 1BNI T16S 72.10 25.00 6.30 1.70 0.15 Decrease 6 Decrease 8 YES YES YES 2LZM T59S 46.90 41.00 2.00 0.70 -0.03 Decrease 8 Decrease 8 NO YES YES 2LZM T59S 46.90 63.00 6.50 0.20 -0.03 Decrease 6 Decrease 8 NO YES YES 2LZM T26S 2.90 65.00 5.40 -0.57 0.83 Decrease 7 Decrease 9 NO NO NO 2LZM T157S 35.30 42.00 2.00 0.66 0.22 Decrease 7 Decrease 9 YES YES YES 1C9O T31S 72.10 70.00 7.00 -0.17 0.17 Increase 5 Decrease 5 NO NO YES 1BNI T6S 49.00 25.00 6.30 0.22 0.03 Decrease 9 Decrease 8 YES YES YES 1STN T33S 29.60 20.00 7.00 1.40 0.96 Decrease 9 Decrease 9 YES YES YES 4LYZ T40S 0.70 74.00 6.40 0.27 0.64 Decrease 9 Decrease 8 YES YES YES 2LZM T152S 0.00 40.00 3.00 2.60 1.05 Decrease 9 Decrease 7 YES YES YES 2LZM T152S 0.00 59.00 5.40 2.00 1.05 Decrease 7 Decrease 8 YES YES YES 2LZM T151S 25.20 65.00 5.40 -0.39 0.22 Decrease 1 Decrease 6 NO NO NO 2CI2 T55S 41.80 25.00 6.20 0.02 0.50 Decrease 7 Decrease 6 YES YES YES 2LZM S38D 46.90 40.00 2.00 0.10 -0.03 Increase 2 Increase 5 NO NO NO 2LZM S38D 46.90 53.00 3.00 -0.22 -0.03 Increase 7 Increase 6 YES YES YES 2LZM S38D 46.90 66.00 6.90 -0.60 -0.03 Increase 9 Increase 9 YES YES YES 2LZM S38D 46.90 66.00 6.90 -0.60 -0.03 Increase 9 Increase 9 YES YES YES 2LZM S44D 59.70 51.00 3.00 0.11 0.84 Increase 6 Increase 7 YES NO NO 1C9O S24D 88.70 70.00 7.00 -0.22 0.18 Increase 6 Increase 2 NO YES YES 1POH S46D 22.20 30.00 7.00 -1.50 -1.43 Decrease 7 Decrease 9 YES NO NO 4LYZ S91D 0.00 74.00 6.40 2.31 1.79 Decrease 7 Decrease 9 YES YES YES 2LZM S38N 46.90 39.00 2.00 0.10 -1.10 Decrease 3 Decrease 4 NO YES YES 2LZM S38N 46.90 62.00 6.70 -0.00 -1.10 Increase 5 Increase 4 NO NO NO 2LZM S44N 59.70 51.00 3.00 0.14 -0.14 Increase 1 Increase 0 NO NO NO 1POH S46N 22.20 30.00 7.00 -0.50 -1.07 Decrease 7 Decrease 7 YES NO NO 1BNI S28E 69.10 25.00 6.30 -0.40 2.22 Increase 6 Increase 3 NO YES YES 2LZM S44E 59.70 51.00 3.00 -0.00 1.71 Increase 6 Increase 6 NO NO NO 2LZM S44Q 59.70 51.00 3.00 -0.27 0.29 Increase 8 Increase 3 NO YES YES 2LZM S44K 59.70 51.00 3.00 -0.20 -0.14 Increase 1 Decrease 1 YES NO YES 2LZM S44R 59.70 51.00 3.00 -0.24 0.76 Increase 8 Increase 9 NO YES YES 2LZM S44H 59.70 51.00 3.00 -0.04 -0.07 Increase 2 Decrease 1 YES NO YES 2LZM S90H 29.90 28.00 2.00 1.00 0.23 Decrease 8 Decrease 9 YES YES YES 2LZM S90H 29.90 65.00 5.50 1.10 0.23 Decrease 7 Decrease 7 YES YES YES 2LZM S90H 29.90 65.00 5.50 1.10 0.23 Decrease 7 Decrease 7 YES YES YES 2LZM S44C 59.70 51.00 3.00 0.11 0.53 Increase 8 Increase 9 YES NO NO 1VQB S67C 0.00 25.00 7.00 3.70 -0.40 Decrease 8 Decrease 9 NO YES YES 2LZM S44T 59.70 51.00 3.00 -0.01 -0.11 Increase 6 Increase 1 YES YES YES 4LYZ S91T 0.00 74.00 6.40 -0.99 -0.13 Decrease 5 Decrease 8 YES NO NO 2RN2 S68T 1.70 49.00 3.00 0.20 -1.32 Decrease 3 Increase 1 NO NO YES 1VQB S67T 0.00 25.00 7.00 1.60 -1.35 Decrease 9 Decrease 9 NO YES YES 1ROP D30P 96.50 69.00 7.00 1.60 -1.51 Increase 5 Increase 7 NO NO NO 1LZ1 D91P 41.60 68.00 2.80 0.40 -1.14 Decrease 4 Decrease 2 NO YES YES 2LZM D72P 55.50 38.00 2.00 2.60 -1.36 Decrease 5 Decrease 5 NO YES YES 2LZM D72P 55.50 63.00 6.50 2.70 -1.36 Decrease 3 Decrease 5 NO YES YES 2RN2 Q113P 58.80 49.00 3.00 0.20 -1.14 Decrease 2 Decrease 1 NO YES YES 2RN2 Q113P 58.80 52.00 5.50 0.60 -1.14 Decrease 1 Decrease 1 NO YES YES 2LZM Q69P 55.40 38.00 2.00 3.30 -1.70 Decrease 2 Decrease 2 NO YES YES 2LZM Q69P 55.40 63.00 6.50 2.90 -1.70 Decrease 0 Increase 5 NO NO YES 2LZM K60P 51.00 41.00 2.00 -0.10 -1.20 Increase 3 Increase 2 YES YES YES 2LZM K60P 51.00 64.00 6.50 -0.00 -1.20 Increase 7 Increase 6 NO NO NO 2RN2 H62P 73.70 50.00 3.00 -1.00 -0.77 Increase 2 Decrease 0 YES NO YES 2RN2 H62P 73.70 50.00 3.00 -1.00 -0.77 Increase 2 Decrease 0 YES NO YES 2RN2 H62P 73.70 52.00 5.50 -1.10 -0.77 Increase 3 Increase 0 YES YES YES 1BNI T6P 49.00 25.00 6.30 3.08 -2.10 Decrease 6 Decrease 7 NO YES YES 2LZM S44P 59.70 51.00 3.00 3.03 -1.21 Increase 9 Increase 9 NO NO NO 4LYZ P70N 84.60 20.00 9.50 2.15 1.68 Decrease 8 Decrease 8 YES YES YES 1RTB P93S 71.20 56.00 4.20 2.10 1.55 Decrease 8 Decrease 9 YES YES YES 1PGA D47A 59.70 25.00 7.00 -0.36 0.68 Decrease 2 Decrease 0 NO NO NO 1BPI D50A 41.60 39.00 7.00 0.40 -0.22 Decrease 8 Decrease 7 NO YES YES 1PGA D46A 54.10 25.00 7.00 1.36 0.83 Decrease 1 Decrease 1 YES YES YES 1BPI D3A 84.70 39.00 7.00 -0.20 0.47 Decrease 3 Decrease 3 NO NO NO 2RN2 D134A 37.50 47.00 9.00 -2.00 -0.75 Increase 7 Increase 4 YES YES YES 2RN2 D134A 37.50 50.00 3.00 -0.80 -0.75 Increase 7 Increase 8 YES YES YES 2RN2 D134A 37.50 53.00 5.50 -1.51 -0.75 Increase 8 Increase 8 YES YES YES 1BVC D44A 81.90 25.00 4.00 0.15 0.19 Decrease 1 Decrease 1 YES YES YES 2ABD D21A 22.20 5.00 5.30 -0.42 -1.14 Decrease 8 Decrease 7 YES NO NO 2LZM D20A 38.90 65.00 5.40 0.30 -1.13 Increase 8 Increase 9 NO NO NO 1BNI D54A 22.20 25.00 6.30 3.00 0.74 Decrease 5 Decrease 5 YES YES YES 1ROP D30A 96.50 69.00 7.00 -0.30 -0.13 Decrease 0 Increase 1 YES YES NO 1STN D83A 23.60 20.00 7.00 3.90 1.32 Decrease 7 Decrease 7 YES YES YES 4LYZ D101A 72.20 74.00 6.40 -0.76 -0.33 Increase 9 Increase 9 YES YES YES 1BNI D8A 65.20 25.00 4.40 0.69 -0.41 Decrease 7 Decrease 8 NO YES YES 1BNI D8A 65.20 25.00 6.30 0.90 -0.41 Decrease 7 Decrease 8 NO YES YES 1BNI D12A 59.70 25.00 6.30 0.30 -0.36 Decrease 5 Decrease 5 NO YES YES 1BNI D12A 59.70 25.00 6.30 -0.43 -0.36 Decrease 5 Decrease 7 YES NO NO 2LZM D47A 24.30 51.00 3.00 0.28 -1.10 Decrease 6 Decrease 2 NO YES YES 2LZM D47A 24.30 62.00 6.70 0.95 -1.10 Decrease 2 Decrease 2 NO YES YES 1STN D95A 45.10 20.00 7.00 3.60 0.46 Decrease 6 Decrease 8 YES YES YES 2RN2 D70A 40.20 47.00 9.00 -1.10 -0.71 Increase 5 Increase 5 YES YES YES 2RN2 D70A 40.20 50.00 3.00 0.10 -0.71 Increase 5 Increase 9 NO NO NO 2CI2 D64A 26.40 25.00 6.20 0.80 0.35 Decrease 7 Decrease 7 YES YES YES 2RN2 D10A 9.70 47.00 9.00 -4.00 -1.18 Increase 8 Increase 8 YES YES YES 2RN2 D10A 9.70 50.00 3.00 -2.40 -1.18 Increase 7 Increase 8 YES YES YES 1BVC D60A 38.90 25.00 4.00 0.10 -0.24 Decrease 6 Decrease 5 NO YES YES 1STN D77A 2.10 20.00 7.00 3.20 3.18 Decrease 8 Decrease 7 YES YES YES 2CI2 D42A 50.00 25.00 6.20 0.96 0.93 Decrease 5 Decrease 6 YES YES YES 1RN1 D76A 1.40 15.00 7.00 3.70 1.71 Decrease 9 Decrease 9 YES YES YES 2CI2 D71A 46.50 25.00 6.20 3.41 0.44 Decrease 8 Decrease 8 YES YES YES 1RTB D121A 8.30 25.00 1.20 0.72 0.89 Decrease 9 Decrease 9 YES YES YES 1RTB D121A 8.30 25.00 6.00 2.20 0.89 Decrease 9 Decrease 9 YES YES YES 1BNI N84A 31.40 25.00 6.30 2.00 0.31 Decrease 3 Decrease 2 YES YES YES 1BPI N24A 28.70 39.00 7.00 2.20 1.94 Decrease 8 Decrease 8 YES YES YES 1BNI N58A 16.40 25.00 6.30 2.70 1.12 Decrease 4 Decrease 3 YES YES YES 2LZM N40A 84.70 51.00 3.00 -0.43 -0.47 Increase 7 Increase 9 YES YES YES 2LZM N40A 84.70 53.00 5.50 -0.20 -0.47 Increase 8 Increase 8 YES YES YES 2LZM N40A 84.70 62.00 6.70 -0.32 -0.47 Increase 9 Increase 8 YES YES YES 1LZ1 N118A 110.00 64.00 2.70 -0.19 -0.05 Increase 4 Increase 7 YES YES YES 1RN1 N36A 59.40 25.00 7.00 -0.03 -0.77 Increase 9 Increase 7 YES YES YES 1RN1 N36A 59.40 50.00 7.00 -0.00 -0.77 Increase 10 Increase 9 NO NO NO 1BPI N44A 13.70 39.00 7.00 3.30 0.45 Decrease 9 Decrease 9 YES YES YES 1RN1 N9A 25.30 25.00 7.00 0.90 2.53 Decrease 9 Decrease 9 YES YES YES 1RN1 N9A 25.30 50.00 7.00 0.71 2.53 Decrease 8 Decrease 9 YES YES YES 1RN1 N44A 18.40 25.00 7.00 2.08 0.79 Decrease 8 Decrease 7 YES YES YES 1RN1 N44A 18.40 50.00 7.00 1.86 0.79 Decrease 6 Decrease 4 YES YES YES 1BNI N77A 50.50 25.00 6.30 1.60 0.22 Decrease 9 Decrease 9 YES YES YES 1BNI N5A 13.00 25.00 6.30 1.90 0.52 Decrease 9 Decrease 9 YES YES YES 2LZM N68A 62.20 47.00 2.50 0.05 -0.40 Decrease 4 Decrease 5 NO YES YES 1BNI N23A 11.60 25.00 6.30 2.20 0.17 Decrease 9 Decrease 8 YES YES YES 2LZM N116A 58.70 51.00 3.00 -0.17 -1.05 Increase 5 Increase 5 YES YES YES 1RN1 N81A 1.40 25.00 7.00 2.87 3.56 Decrease 8 Decrease 9 YES YES YES 1RN1 N81A 1.40 50.00 7.00 2.91 3.56 Decrease 7 Decrease 7 YES YES YES 1SAR N39A 11.60 48.00 7.00 2.20 0.03 Decrease 7 Decrease 5 YES YES YES 2CI2 N75A 32.80 25.00 6.20 0.83 -0.36 Decrease 6 Decrease 7 NO YES YES 2LZM N101A 0.00 59.00 5.40 1.50 2.91 Decrease 6 Decrease 5 YES YES YES 1BPI E49A 73.30 39.00 7.00 0.20 -0.29 Decrease 5 Decrease 6 NO YES YES 2ABD E67A 61.20 5.00 5.30 0.36 -0.66 Decrease 2 Increase 6 NO NO YES 1BPI E7A 70.40 39.00 7.00 1.50 0.18 Decrease 5 Decrease 5 YES YES YES 2LZM E45A 36.60 51.00 3.00 -0.55 0.82 Decrease 0 Decrease 5 NO NO NO 2LZM E45A 36.60 62.00 6.70 -0.01 0.82 Increase 4 Increase 1 NO YES YES 2LZM E128A 55.50 40.00 2.00 -0.16 -0.34 Decrease 1 Decrease 6 YES NO NO 1BNI E29A 55.00 25.00 6.30 1.25 0.94 Decrease 4 Decrease 3 YES YES YES 1BNI E73A 7.40 25.00 6.30 2.50 0.22 Decrease 9 Decrease 9 YES YES YES 1BVC E109A 61.80 4.00 4.20 -0.36 -0.03 Decrease 4 Decrease 5 YES NO NO 2CI2 E60A 56.10 25.00 6.20 0.70 -0.04 Decrease 7 Decrease 8 NO YES YES 2CI2 E60A 56.10 25.00 6.30 0.68 -0.04 Decrease 7 Decrease 6 NO YES YES 2CI2 E45A 56.10 25.00 6.20 0.32 -0.27 Decrease 7 Decrease 8 NO YES YES 2LZM E11A 21.20 66.00 5.40 -1.10 0.57 Increase 3 Increase 3 NO YES YES 1BVC E4A 59.50 25.00 4.00 0.70 0.22 Decrease 4 Increase 0 YES NO YES 2RN2 E48A 12.00 47.00 9.00 0.30 2.25 Decrease 2 Decrease 4 YES YES YES 2RN2 E48A 12.00 50.00 3.00 0.10 2.25 Decrease 3 Decrease 4 YES YES YES 2CI2 E26A 52.10 25.00 6.20 0.47 -0.69 Decrease 5 Decrease 4 NO YES YES 1RN1 E58A 6.30 25.00 7.00 0.77 0.30 Decrease 8 Decrease 9 YES YES YES 1RN1 E58A 6.30 48.00 7.00 0.78 0.30 Decrease 5 Decrease 6 YES YES YES 1C9O E46A 38.40 70.00 7.00 0.22 0.56 Decrease 3 Decrease 3 YES YES YES 1STN E73A 32.10 20.00 7.00 1.60 0.53 Decrease 7 Decrease 7 YES YES YES 1BVC E18A 54.40 25.00 4.00 0.70 0.93 Decrease 3 Decrease 3 YES YES YES 1BNI Q104A 47.60 25.00 6.30 0.20 0.92 Decrease 5 Decrease 3 YES YES YES 1BPI Q31A 39.80 39.00 7.00 1.00 1.40 Decrease 8 Decrease 9 YES YES YES 2CI2 Q41A 86.20 25.00 6.20 0.02 0.34 Decrease 3 Decrease 3 YES YES YES 2ABD Q33A 0.60 5.00 5.30 3.66 0.77 Decrease 9 Decrease 9 YES YES YES 2LZM Q123A 56.00 51.00 3.00 0.22 -0.63 Decrease 0 Decrease 0 NO YES YES 2LZM Q122A 52.10 51.00 3.00 0.24 -0.07 Decrease 4 Decrease 6 NO YES YES 1BNI Q31A 65.50 25.00 6.30 -0.10 0.12 Decrease 4 Decrease 6 NO NO NO 1LZ1 Q58A 3.90 64.00 2.70 -0.91 2.99 Decrease 7 Decrease 8 NO NO NO 1BVC Q8A 48.70 4.00 4.20 -1.07 -0.16 Decrease 4 Decrease 3 YES NO NO 2LZM Q105A 31.90 42.00 2.10 0.90 0.72 Decrease 7 Decrease 7 YES YES YES 2LZM Q105A 31.90 66.00 5.80 0.60 0.72 Decrease 3 Decrease 1 YES YES YES 1BPI K41A 49.10 39.00 7.00 0.40 0.59 Decrease 0 Increase 5 YES NO YES 1BPI K46A 82.20 39.00 7.00 -0.10 -1.14 Increase 1 Decrease 0 YES NO YES 1BNI K66A 63.70 25.00 6.30 -0.20 -0.70 Increase 8 Increase 6 YES YES YES 1BPI K26A 99.70 39.00 7.00 -0.00 -0.36 Decrease 0 Decrease 2 NO NO NO 2ABD K54A 22.40 5.00 5.30 0.86 1.74 Decrease 2 Decrease 2 YES YES YES 2LZM K48A 70.50 51.00 3.00 0.32 0.35 Increase 2 Increase 5 YES NO NO 2LZM K48A 70.50 62.00 6.70 0.56 0.35 Increase 4 Increase 2 YES NO NO 1BPI K15A 91.90 39.00 7.00 0.40 -0.23 Decrease 0 Increase 2 NO NO YES 1PGA K50A 27.20 25.00 7.00 0.45 0.65 Decrease 3 Decrease 1 YES YES YES 1BVC K56A 36.50 25.00 4.00 0.25 -0.49 Decrease 1 Increase 2 NO NO YES 2LZM K43A 20.90 51.00 3.00 0.96 -0.03 Decrease 5 Decrease 4 NO YES YES 2LZM K43A 20.90 53.00 5.50 1.10 -0.03 Decrease 4 Decrease 3 NO YES YES 2LZM K43A 20.90 62.00 6.70 1.03 -0.03 Decrease 1 Increase 1 NO NO YES 1BVC K140A 66.10 4.00 4.20 -0.60 -0.08 Decrease 3 Decrease 6 YES NO NO 2RN2 K95A 68.10 49.00 3.00 -0.10 0.14 Increase 2 Decrease 0 NO NO YES 2RN2 K95A 68.10 49.00 3.00 -0.10 0.14 Increase 2 Decrease 0 NO NO YES 2ABD K32A 28.20 5.00 5.30 1.02 1.01 Decrease 1 Decrease 4 YES YES YES 2CI2 K37A 66.10 25.00 6.20 -0.21 0.16 Decrease 3 Decrease 3 NO NO NO 2CI2 K37A 66.10 46.00 6.30 -0.23 0.16 Decrease 3 Decrease 1 NO NO NO 2CI2 K43A 4.40 25.00 6.20 0.65 1.61 Decrease 8 Decrease 9 YES YES YES 2CI2 K43A 4.40 25.00 6.20 0.65 1.61 Decrease 8 Decrease 9 YES YES YES 1BVC K77A 51.50 25.00 4.00 0.05 0.88 Decrease 1 Decrease 0 YES YES YES 2CI2 K21A 39.40 25.00 6.20 0.55 0.80 Decrease 4 Decrease 4 YES YES YES 2CI2 K30A 39.90 25.00 6.20 -0.42 1.61 Decrease 3 Decrease 4 NO NO NO 2CI2 K36A 46.20 25.00 6.20 0.49 0.92 Decrease 5 Decrease 2 YES YES YES 2CI2 K36A 46.20 25.00 6.20 0.49 0.92 Decrease 5 Decrease 2 YES YES YES 1LZ1 R50A 66.80 64.00 2.70 -0.43 0.39 Increase 8 Increase 9 NO YES YES 1BPI R39A 87.80 39.00 7.00 -0.00 0.11 Increase 1 Decrease 3 NO NO NO 1BPI R53A 79.90 39.00 7.00 0.10 -0.25 Decrease 6 Decrease 7 NO YES YES 1BPI R42A 72.50 39.00 7.00 0.50 0.75 Decrease 7 Decrease 7 YES YES YES 1BPI R1A 69.40 39.00 7.00 0.50 1.17 Decrease 6 Decrease 7 YES YES YES 1BPI R17A 96.90 39.00 7.00 0.30 0.21 Decrease 5 Decrease 5 YES YES YES 1BPI R20A 18.80 39.00 7.00 1.80 0.50 Decrease 9 Decrease 9 YES YES YES 1BNI R110A 27.90 25.00 6.30 0.40 0.92 Decrease 8 Decrease 9 YES YES YES 1LZ1 R21A 67.70 64.00 2.70 -1.32 0.13 Increase 5 Increase 3 NO YES YES 2CI2 R62A 51.10 25.00 6.20 0.58 0.34 Decrease 7 Decrease 6 YES YES YES 2LZM R119A 49.80 51.00 3.00 0.18 -1.20 Decrease 4 Decrease 3 NO YES YES 1C9O R3A 71.60 70.00 7.00 1.89 0.74 Decrease 3 Decrease 3 YES YES YES 1LZ1 H78A 88.00 64.00 2.70 0.14 0.02 Decrease 3 Decrease 3 YES YES YES 1BNI H18A 59.40 25.00 6.30 1.85 0.74 Decrease 6 Decrease 6 YES YES YES 1RN1 H92A 29.10 25.00 6.00 0.62 0.94 Decrease 5 Decrease 3 YES YES YES 1BVC H116A 48.40 82.00 9.60 -0.20 -0.40 Increase 5 Increase 0 YES YES YES 1RTB H119A 38.50 25.00 1.20 -1.10 0.96 Decrease 8 Decrease 6 NO NO NO 1RTB H119A 38.50 25.00 6.00 -0.20 0.96 Decrease 8 Decrease 9 NO NO NO 1BTA C82A 26.40 25.00 7.40 -0.48 -0.16 Decrease 6 Decrease 8 YES NO NO 4LYZ C94A 2.10 20.00 9.50 4.78 0.26 Decrease 9 Decrease 9 YES YES YES 1LZ1 C77A 15.70 57.00 3.00 4.60 0.56 Decrease 8 Decrease 6 YES YES YES 1VQB C33A 0.00 25.00 7.00 0.50 0.57 Decrease 9 Decrease 9 YES YES YES 1BPI T54A 37.50 39.00 7.00 0.10 0.99 Decrease 8 Decrease 9 YES YES YES 1PGA T49A 59.80 25.00 7.00 0.86 0.16 Decrease 5 Decrease 6 YES YES YES 1BVC T51A 46.90 82.00 9.60 1.40 0.52 Increase 3 Increase 7 YES NO NO 1BNI T26A 23.10 25.00 6.30 1.90 1.30 Decrease 6 Decrease 7 YES YES YES 1BPI T11A 49.70 39.00 7.00 -0.00 0.09 Decrease 6 Decrease 8 NO NO NO 2CI2 T58A 75.00 25.00 6.30 0.69 -0.09 Decrease 3 Decrease 3 NO YES YES 1BPI T32A 62.00 39.00 7.00 0.10 0.34 Decrease 6 Decrease 6 YES YES YES 2ABD T35A 34.60 5.00 5.30 1.09 0.36 Decrease 7 Decrease 7 YES YES YES 1BNI T16A 72.10 25.00 6.30 0.27 0.21 Decrease 4 Decrease 3 YES YES YES 2LZM T59A 46.90 41.00 2.00 2.80 0.39 Decrease 6 Decrease 7 YES YES YES 2LZM T59A 46.90 63.00 6.50 1.50 0.39 Decrease 4 Decrease 4 YES YES YES 2LZM T157A 35.30 38.00 2.00 1.10 1.63 Decrease 6 Decrease 5 YES YES YES 2LZM T157A 35.30 42.00 2.00 1.40 1.63 Decrease 5 Decrease 7 YES YES YES 2LZM T157A 35.30 46.00 2.50 0.90 1.63 Decrease 5 Decrease 5 YES YES YES 2LZM T157A 35.30 53.00 3.00 0.50 1.63 Decrease 4 Decrease 3 YES YES YES 1BNI T6A 49.00 25.00 6.30 2.10 0.29 Decrease 7 Decrease 7 YES YES YES 2LZM T115A 63.40 51.00 3.00 0.14 -0.30 Decrease 2 Decrease 2 NO YES YES 2LZM T152A 0.00 59.00 5.40 1.50 0.61 Decrease 6 Decrease 5 YES YES YES 2CI2 T22A 41.10 25.00 6.30 0.85 0.29 Decrease 5 Decrease 3 YES YES YES 2CI2 T22A 41.10 25.00 6.30 0.85 0.29 Decrease 5 Decrease 3 YES YES YES 1BVC T67A 62.00 82.00 9.60 0.30 -0.01 Decrease 2 Decrease 3 NO YES YES 2CI2 T55A 41.80 25.00 6.20 -0.23 0.76 Decrease 4 Decrease 5 NO NO NO 1IOB T9A 4.30 25.00 6.50 0.80 0.76 Decrease 9 Decrease 9 YES YES YES 1STN T62A 0.00 20.00 7.00 2.40 0.80 Decrease 7 Decrease 5 YES YES YES 1BPI S47A 23.90 39.00 7.00 1.60 0.11 Decrease 8 Decrease 6 YES YES YES 1BNI S28A 69.10 25.00 6.30 -0.41 0.42 Increase 6 Increase 0 NO YES YES 1BNI S85A 29.90 25.00 6.30 0.12 -0.40 Decrease 6 Decrease 6 NO YES YES 2LZM S44A 59.70 47.00 2.50 0.44 0.16 Increase 5 Increase 7 YES NO NO 2LZM S44A 59.70 51.00 3.00 -0.44 0.16 Increase 6 Increase 8 NO YES YES 2LZM S44A 59.70 62.00 6.70 -0.34 0.16 Increase 8 Increase 9 NO YES YES 1BNI S92A 45.20 25.00 4.40 2.83 1.06 Decrease 2 Decrease 1 YES YES YES 1BNI S92A 45.20 25.00 6.30 2.80 1.06 Decrease 2 Decrease 3 YES YES YES 1BNI S91A 1.70 25.00 4.40 1.38 2.07 Decrease 7 Decrease 8 YES YES YES 1BNI S91A 1.70 25.00 6.30 1.90 2.07 Decrease 7 Decrease 7 YES YES YES 1RN1 S64A 69.10 25.00 7.00 1.44 -0.22 Decrease 6 Decrease 6 NO YES YES 1RN1 S64A 69.10 50.00 7.00 1.56 -0.22 Decrease 5 Decrease 4 NO YES YES 1BVC S117A 58.00 82.00 9.60 0.30 -0.15 Decrease 1 Decrease 1 NO YES YES 1POH S46A 22.20 30.00 7.00 0.90 -0.03 Decrease 7 Decrease 8 NO YES YES 4LYZ S91A 0.00 74.00 6.40 0.15 0.84 Decrease 7 Decrease 6 YES YES YES 1RN1 S12A 30.70 25.00 7.00 1.23 1.69 Decrease 9 Decrease 8 YES YES YES 1RN1 S12A 30.70 50.00 7.00 1.08 1.69 Decrease 8 Decrease 8 YES YES YES 2LZM S117A 1.70 51.00 3.00 -1.27 -0.70 Decrease 3 Decrease 4 YES NO NO 1RN1 S17A 53.80 25.00 7.00 -0.67 -0.95 Decrease 6 Decrease 9 YES NO NO 1RN1 S17A 53.80 50.00 7.00 -0.57 -0.95 Decrease 4 Decrease 7 YES NO NO 2RN2 S68A 1.70 49.00 3.00 0.50 0.08 Decrease 4 Decrease 5 YES YES YES 2CI2 S31A 16.20 25.00 3.00 -1.00 0.08 Decrease 7 Decrease 8 NO NO NO 2CI2 S31A 16.20 25.00 6.20 0.89 0.08 Decrease 7 Decrease 6 YES YES YES 2CI2 S31A 16.20 25.00 6.20 0.89 0.08 Decrease 7 Decrease 6 YES YES YES 1BPI P8A 62.70 39.00 7.00 0.30 1.20 Decrease 8 Decrease 8 YES YES YES 1RTB P93A 71.20 56.00 4.20 2.70 1.19 Decrease 8 Decrease 7 YES YES YES 1BPI P2A 40.90 39.00 7.00 1.30 0.75 Decrease 9 Decrease 9 YES YES YES 2ABD P44A 34.50 5.00 5.30 1.40 1.49 Decrease 9 Decrease 9 YES YES YES 1BVC P88A 57.80 82.00 9.60 -0.60 1.31 Increase 6 Increase 4 NO YES YES 1BPI P13A 47.90 39.00 7.00 1.20 1.17 Decrease 9 Decrease 9 YES YES YES 1BPI P9A 33.10 39.00 7.00 0.80 1.31 Decrease 9 Decrease 9 YES YES YES 1RTB P114A 66.20 56.00 4.20 3.20 0.19 Decrease 8 Decrease 8 YES YES YES 2CI2 P44A 70.50 25.00 6.20 1.76 2.21 Decrease 9 Decrease 9 YES YES YES 2ABD P19A 6.30 5.00 5.30 1.07 2.63 Decrease 9 Decrease 9 YES YES YES 2CI2 P25A 45.10 25.00 6.20 1.57 2.13 Decrease 8 Decrease 7 YES YES YES 2CI2 P52A 54.30 25.00 6.20 0.17 2.24 Decrease 9 Decrease 8 YES YES YES 2CI2 P80A 2.10 25.00 6.20 3.34 3.30 Decrease 9 Decrease 9 YES YES YES 2LZM A41D 29.00 65.00 5.40 -0.29 -0.02 Increase 2 Increase 0 YES YES YES 1BNI A32D 78.90 25.00 6.30 0.70 1.21 Decrease 4 Decrease 3 YES YES YES 1RN1 A21D 51.70 0.00 2.50 -0.33 0.71 Decrease 8 Decrease 9 NO NO NO 1RN1 A21D 51.70 0.00 7.00 0.71 0.71 Decrease 7 Decrease 9 YES YES YES 2RN2 A52D 0.00 53.00 3.20 1.90 -1.96 Decrease 5 Decrease 3 NO YES YES 1BNI A32N 78.90 25.00 6.30 0.70 -0.32 Decrease 5 Decrease 3 NO YES YES 1RN1 A21N 51.70 0.00 2.50 -0.34 0.23 Decrease 7 Decrease 8 NO NO NO 2RN2 A52N 0.00 53.00 3.20 1.80 -4.49 Decrease 5 Decrease 6 NO YES YES 1BNI A32E 78.90 25.00 6.30 0.60 1.93 Decrease 4 Decrease 3 YES YES YES 1RN1 A21E 51.70 0.00 2.50 -0.05 2.03 Decrease 7 Decrease 9 NO NO NO 1RN1 A21E 51.70 0.00 7.00 0.69 2.03 Decrease 7 Decrease 7 YES YES YES 2RN2 A52E 0.00 53.00 3.20 1.50 1.78 Decrease 5 Decrease 6 YES YES YES 1BNI A32Q 78.90 25.00 6.30 0.50 1.16 Decrease 3 Decrease 5 YES YES YES 1RN1 A21Q 51.70 0.00 2.50 0.26 0.36 Decrease 8 Decrease 9 YES YES YES 1RN1 A21Q 51.70 0.00 7.00 0.40 0.36 Decrease 8 Decrease 9 YES YES YES 2RN2 A52Q 0.00 53.00 3.20 1.20 -1.31 Decrease 5 Decrease 5 NO YES YES 2LZM A42K 0.00 53.00 5.50 3.70 -1.15 Decrease 9 Decrease 9 NO YES YES 1BNI A32K 78.90 25.00 6.30 0.20 -0.34 Decrease 6 Decrease 8 NO YES YES 1RN1 A21K 51.70 0.00 2.50 0.51 0.88 Decrease 8 Decrease 9 YES YES YES 1BVC A130K 0.00 4.00 7.80 2.10 -2.12 Decrease 9 Decrease 9 NO YES YES 2RN2 A52K 0.00 53.00 3.20 5.90 0.19 Decrease 7 Decrease 7 YES YES YES 1BNI A32R 78.90 25.00 6.30 0.10 0.81 Decrease 2 Increase 2 YES NO YES 1RN1 A21R 51.70 0.00 2.50 0.41 -0.02 Decrease 7 Decrease 9 NO YES YES 1BNI A32H 78.90 25.00 6.30 0.80 -0.44 Decrease 6 Decrease 6 NO YES YES 1RN1 A21H 51.70 0.00 2.50 0.56 0.75 Decrease 8 Decrease 8 YES YES YES 1RN1 A21H 51.70 0.00 7.00 0.17 0.75 Decrease 8 Decrease 7 YES YES YES 2RN2 A52H 0.00 53.00 3.20 3.60 -3.71 Decrease 6 Decrease 5 NO YES YES 1BNI A32C 78.90 25.00 6.30 1.00 0.27 Decrease 1 Increase 6 YES NO YES 1RN1 A21C 51.70 0.00 2.50 0.74 0.73 Decrease 7 Decrease 9 YES YES YES 2RN2 A52C 0.00 53.00 3.20 -0.80 0.19 Decrease 3 Decrease 2 NO NO NO 2RN2 A125T 57.20 49.00 3.00 -0.10 0.23 Increase 9 Increase 4 NO YES YES 2RN2 A125T 57.20 52.00 5.50 -0.00 0.23 Increase 9 Increase 10 NO NO NO 2LZM A146T 0.00 47.00 3.00 2.29 -2.80 Decrease 7 Decrease 7 NO YES YES 2LZM A146T 0.00 70.00 6.50 1.50 -2.80 Decrease 5 Decrease 1 NO YES YES 2LZM A93T 65.30 65.00 5.40 -0.06 0.55 Increase 5 Increase 8 NO YES YES 2LZM A160T 14.50 65.00 6.00 1.65 -0.21 Decrease 6 Decrease 7 NO YES YES 1BNI A32T 78.90 25.00 6.30 0.80 -0.07 Decrease 2 Decrease 0 NO YES YES 1HFY A30T 0.00 20.00 2.00 -0.06 -0.91 Decrease 9 Decrease 9 YES NO NO 1RN1 A21T 51.70 0.00 2.50 0.57 0.26 Decrease 9 Decrease 9 YES YES YES 1VQB A86T 90.70 25.00 7.00 0.70 0.76 Decrease 7 Decrease 7 YES YES YES 2RN2 A52T 0.00 53.00 3.20 0.80 -0.76 Decrease 5 Decrease 0 NO YES YES 5CRO A36S 58.10 45.00 3.00 -0.40 -0.09 Increase 4 Increase 4 YES YES YES 2LZM A41S 29.00 51.00 3.00 0.60 -0.80 Decrease 6 Decrease 7 NO YES YES 2LZM A49S 39.90 51.00 3.00 0.50 1.42 Decrease 7 Decrease 8 YES YES YES 2LZM A134S 23.60 51.00 3.00 0.10 -0.12 Decrease 5 Decrease 5 NO YES YES 2LZM A93S 65.30 51.00 3.00 0.20 0.45 Decrease 3 Decrease 0 YES YES YES 2LZM A82S 78.90 51.00 3.00 0.30 0.21 Decrease 5 Decrease 3 YES YES YES 2LZM A42S 0.00 51.00 3.00 2.30 1.54 Decrease 9 Decrease 8 YES YES YES 1BNI A32S 78.90 25.00 6.30 0.40 -0.05 Decrease 6 Decrease 4 NO YES YES 2LZM A130S 7.30 51.00 3.00 1.00 0.57 Decrease 7 Decrease 7 YES YES YES 1RN1 A21S 51.70 0.00 2.50 0.49 0.33 Decrease 9 Decrease 9 YES YES YES 1RN1 A21S 51.70 0.00 7.00 0.40 0.33 Decrease 8 Decrease 8 YES YES YES 2LZM A73S 39.90 51.00 3.00 0.40 0.66 Decrease 8 Decrease 7 YES YES YES 2RN2 A52S 0.00 53.00 3.20 1.80 0.38 Decrease 7 Decrease 5 YES YES YES 2LZM A98S 0.00 51.00 3.00 2.50 1.83 Decrease 9 Decrease 9 YES YES YES 1STN A90S 0.00 20.00 7.00 2.00 0.56 Decrease 9 Decrease 9 YES YES YES 1STN A90S 0.00 47.00 5.00 2.60 0.56 Decrease 9 Decrease 9 YES YES YES 1STN A90S 0.00 51.00 7.00 2.50 0.56 Decrease 8 Decrease 9 YES YES YES 1LZ1 A47P 71.70 68.00 2.80 -0.10 -1.69 Increase 10 Increase 10 YES YES YES 2LZM A93P 65.30 38.00 2.00 -0.03 -0.86 Increase 5 Increase 5 YES YES YES 2LZM A93P 65.30 41.00 2.00 -0.10 -0.86 Increase 6 Increase 7 YES YES YES 2LZM A93P 65.30 46.00 2.50 -0.51 -0.86 Increase 8 Increase 8 YES YES YES 2LZM A93P 65.30 53.00 3.00 -1.10 -0.86 Increase 9 Increase 9 YES YES YES 2LZM A93P 65.30 41.00 2.00 -0.10 -0.86 Increase 6 Increase 7 YES YES YES 2LZM A82P 78.90 38.00 2.00 0.07 -1.17 Increase 2 Increase 5 NO NO NO 2LZM A82P 78.90 41.00 2.00 -0.30 -1.17 Increase 3 Increase 1 YES YES YES 2LZM A82P 78.90 46.00 2.50 -0.51 -1.17 Increase 5 Increase 2 YES YES YES 2LZM A82P 78.90 53.00 3.00 -1.27 -1.17 Increase 6 Increase 7 YES YES YES 2LZM A82P 78.90 64.00 6.50 -0.80 -1.17 Increase 8 Increase 9 YES YES YES 2LZM A82P 78.90 66.00 5.40 -0.57 -1.17 Increase 8 Increase 8 YES YES YES 1BNI A32P 78.90 25.00 6.30 4.10 -1.51 Increase 1 Increase 5 NO NO NO 2LZM A74P 7.30 57.00 3.50 5.70 -1.92 Decrease 9 Decrease 8 NO YES YES 2LZM A74P 7.30 62.00 4.00 5.00 -1.92 Decrease 8 Decrease 9 NO YES YES 2LZM A74P 7.30 62.00 6.50 4.60 -1.92 Decrease 8 Decrease 8 NO YES YES 2LZM A74P 7.30 65.00 5.50 4.50 -1.92 Decrease 8 Decrease 9 NO YES YES 2RN2 A52P 0.00 53.00 3.20 1.60 -2.87 Decrease 1 Increase 4 NO NO YES 1ROP D30G 96.50 69.00 7.00 -2.00 -0.05 Increase 7 Increase 3 YES YES YES 1STN D83G 23.60 20.00 7.00 2.80 1.45 Decrease 8 Decrease 9 YES YES YES 4LYZ D101G 72.20 74.00 6.40 -0.45 -0.01 Increase 8 Increase 6 YES YES YES 1BNI D8G 65.20 25.00 6.30 1.17 0.62 Decrease 9 Decrease 8 YES YES YES 1BNI D12G 59.70 25.00 4.40 0.78 0.75 Decrease 8 Decrease 9 YES YES YES 1BNI D12G 59.70 25.00 6.30 1.29 0.75 Decrease 8 Decrease 8 YES YES YES 1STN D95G 45.10 20.00 7.00 3.10 0.88 Decrease 8 Decrease 9 YES YES YES 1STN D77G 2.10 20.00 7.00 2.20 1.54 Decrease 9 Decrease 9 YES YES YES 1LZ1 N118G 110.00 64.00 2.70 -0.05 -0.05 Increase 6 Increase 5 YES YES YES 1BPI N44G 13.70 25.00 2.00 4.70 1.24 Decrease 9 Decrease 9 YES YES YES 1BPI N43G 1.40 25.00 2.00 5.70 3.66 Decrease 9 Decrease 9 YES YES YES 2LZM N55G 84.70 41.00 2.00 0.50 -0.50 Decrease 7 Decrease 8 NO YES YES 2LZM N55G 84.70 64.00 6.50 0.60 -0.50 Increase 0 Decrease 4 NO YES NO 1BNI E29G 55.00 25.00 6.30 1.80 2.51 Decrease 7 Decrease 8 YES YES YES 1BVC E109G 61.80 4.00 4.20 0.96 1.15 Decrease 8 Decrease 7 YES YES YES 2CI2 Q41G 86.20 25.00 6.20 0.60 1.25 Decrease 4 Decrease 5 YES YES YES 1BNI Q31G 65.50 25.00 6.30 0.98 1.55 Decrease 7 Decrease 7 YES YES YES 1BVC Q8G 48.70 4.00 4.20 0.63 0.60 Decrease 8 Decrease 8 YES YES YES 2LZM Q105G 31.90 42.00 2.10 1.70 1.74 Decrease 9 Decrease 9 YES YES YES 2LZM Q105G 31.90 66.00 5.80 1.50 1.74 Decrease 6 Decrease 3 YES YES YES 1BNI K27G 26.70 25.00 6.30 0.40 1.38 Decrease 7 Decrease 3 YES YES YES 2LZM K124G 47.20 64.00 6.50 0.10 1.31 Increase 1 Decrease 0 YES YES NO 2RN2 K95G 68.10 49.00 3.00 -1.70 0.35 Increase 5 Increase 2 NO YES YES 2RN2 K95G 68.10 49.00 5.50 -1.90 0.35 Increase 6 Increase 3 NO YES YES 2CI2 K37G 66.10 25.00 6.20 0.99 1.47 Decrease 6 Decrease 6 YES YES YES 2CI2 K37G 66.10 46.00 6.30 0.97 1.47 Decrease 3 Decrease 0 YES YES YES 2CI2 K43G 4.40 25.00 6.20 3.19 3.41 Decrease 9 Decrease 9 YES YES YES 1IOB K97G 41.30 25.00 6.50 1.20 -2.66 Decrease 9 Decrease 9 NO YES YES 2CI2 K36G 46.20 25.00 6.20 2.32 1.95 Decrease 8 Decrease 7 YES YES YES 1LZ1 R21G 67.70 64.00 2.70 -1.15 0.75 Increase 0 Decrease 7 NO NO YES 1ANK R88G 32.30 51.00 7.40 0.20 2.05 Decrease 8 Decrease 6 YES YES YES 1BNI H18G 59.40 25.00 5.80 0.98 1.12 Decrease 9 Decrease 9 YES YES YES 1BNI H18G 59.40 25.00 6.30 0.70 1.12 Decrease 9 Decrease 9 YES YES YES 1BNI H18G 59.40 25.00 9.00 -0.51 1.12 Decrease 9 Decrease 9 NO NO NO 1BNI T26G 23.10 25.00 4.40 2.08 1.87 Decrease 9 Decrease 9 YES YES YES 1BNI T26G 23.10 25.00 6.30 1.50 1.87 Decrease 9 Decrease 9 YES YES YES 1BNI T16G 72.10 25.00 6.30 1.66 1.31 Decrease 7 Decrease 8 YES YES YES 2LZM T59G 46.90 41.00 2.00 2.20 0.74 Decrease 9 Decrease 9 YES YES YES 2LZM T59G 46.90 63.00 6.50 1.60 0.74 Decrease 8 Decrease 8 YES YES YES 2LZM T157G 35.30 42.00 2.00 1.10 1.94 Decrease 8 Decrease 5 YES YES YES 1BNI T6G 49.00 25.00 6.30 1.20 0.73 Decrease 9 Decrease 9 YES YES YES 2CI2 T22G 41.10 25.00 6.30 1.16 0.82 Decrease 8 Decrease 9 YES YES YES 1IOB T9G 4.30 25.00 6.50 2.60 1.49 Decrease 9 Decrease 9 YES YES YES 1STN T62G 0.00 20.00 7.00 3.40 2.49 Decrease 9 Decrease 9 YES YES YES 1BNI S28G 69.10 25.00 6.30 0.45 0.95 Increase 5 Increase 8 YES NO NO 2LZM S44G 59.70 51.00 3.00 0.53 0.86 Increase 1 Increase 6 YES NO NO 2RN2 S68G 1.70 49.00 3.00 2.40 1.52 Decrease 6 Decrease 8 YES YES YES 2CI2 S31G 16.20 25.00 3.50 -0.84 0.57 Decrease 9 Decrease 9 NO NO NO 2CI2 S31G 16.20 25.00 6.20 0.80 0.57 Decrease 9 Decrease 9 YES YES YES 1RTB P93G 71.20 61.00 6.00 2.20 1.58 Decrease 8 Decrease 9 YES YES YES 1LZ1 P71G 47.90 68.00 2.80 1.60 1.95 Decrease 8 Decrease 6 YES YES YES 1RTB P114G 66.20 56.00 4.20 2.80 0.42 Decrease 9 Decrease 9 YES YES YES 1RTB P114G 66.20 61.00 6.00 3.30 0.42 Decrease 9 Decrease 9 YES YES YES 1LZ1 P103G 95.80 68.00 2.80 0.10 0.98 Decrease 6 Decrease 4 YES YES YES 2ABD A34G 8.20 5.00 5.30 1.57 1.99 Decrease 9 Decrease 9 YES YES YES 1STN A60G 52.60 20.00 7.00 1.50 1.19 Decrease 7 Decrease 8 YES YES YES 1BNI A32G 78.90 25.00 6.30 0.90 0.77 Decrease 7 Decrease 7 YES YES YES 2ABD A9G 5.40 5.00 5.30 1.81 1.44 Decrease 9 Decrease 9 YES YES YES 3MBP A276G 0.00 25.00 7.60 1.50 1.56 Decrease 9 Decrease 9 YES YES YES 1RN1 A21G 51.70 0.00 2.50 0.90 1.23 Decrease 9 Decrease 9 YES YES YES 2RN2 A52G 0.00 53.00 3.20 2.70 1.79 Decrease 8 Decrease 8 YES YES YES 2CI2 A77G 41.70 25.00 6.30 1.88 0.93 Decrease 9 Decrease 9 YES YES YES 2CI2 A35G 0.00 25.00 6.20 1.09 2.31 Decrease 9 Decrease 9 YES YES YES 1BNI G34D 44.50 25.00 6.30 3.39 -0.21 Decrease 4 Decrease 5 NO YES YES 2LZM G156D 22.90 41.00 2.00 1.40 -3.41 Decrease 4 Decrease 7 NO YES YES 2LZM G156D 22.90 64.00 6.50 2.30 -3.41 Decrease 2 Decrease 1 NO YES YES 4LYZ G49N 25.40 20.00 9.50 0.96 -0.56 Decrease 7 Decrease 8 NO YES YES 1BNI G34N 44.50 25.00 6.30 2.75 -0.23 Decrease 4 Decrease 3 NO YES YES 2LZM G113E 68.60 65.00 5.40 -0.30 -0.70 Increase 10 Increase 9 YES YES YES 1C9O G23Q 50.80 70.00 7.00 0.29 -0.75 Decrease 0 Decrease 0 NO YES YES 1BNI G34K 44.50 25.00 6.30 3.12 -0.15 Decrease 6 Decrease 6 NO YES YES 4LYZ G102R 80.10 74.00 6.40 -0.38 -0.36 Increase 9 Increase 10 YES YES YES 1BNI G34R 44.50 25.00 6.30 2.42 -0.26 Decrease 2 Decrease 2 NO YES YES 1BNI G34H 44.50 25.00 4.40 2.60 -0.24 Decrease 5 Decrease 6 NO YES YES 1BNI G34H 44.50 25.00 6.30 2.65 -0.24 Decrease 4 Decrease 5 NO YES YES 1BNI G34H 44.50 25.00 8.90 3.15 -0.24 Decrease 4 Decrease 4 NO YES YES 3MBP G19C 0.00 25.00 7.60 2.30 -1.50 Decrease 9 Decrease 8 NO YES YES 1BNI G34T 44.50 25.00 6.30 3.37 -0.13 Decrease 2 Decrease 5 NO YES YES 1BNI G65S 80.10 25.00 6.30 -0.50 0.17 Increase 5 Increase 4 NO YES YES 1STN G79S 22.90 20.00 7.00 2.40 0.37 Decrease 9 Decrease 9 YES YES YES 1STN G79S 22.90 40.00 5.30 1.80 0.37 Decrease 8 Decrease 8 YES YES YES 1STN G79S 22.90 47.00 5.00 1.20 0.37 Decrease 8 Decrease 8 YES YES YES 1STN G79S 22.90 51.00 7.00 1.30 0.37 Decrease 7 Decrease 7 YES YES YES 1BPI G36S 0.00 72.00 4.60 0.70 -2.81 Decrease 6 Decrease 8 NO YES YES 1BNI G34S 44.50 25.00 6.30 3.20 -0.15 Decrease 5 Decrease 3 NO YES YES 1BPI G57A 49.60 39.00 7.00 0.20 -0.03 Decrease 5 Decrease 5 NO YES YES 1BPI G56A 24.10 39.00 7.00 0.20 -0.75 Decrease 6 Decrease 5 NO YES YES 1BPI G28A 48.30 39.00 7.00 1.00 0.16 Decrease 6 Decrease 5 YES YES YES 1BPI G12A 24.10 39.00 7.00 1.80 -1.06 Decrease 6 Decrease 6 NO YES YES 1BPI G37A 45.70 25.00 2.00 4.90 -0.62 Decrease 7 Decrease 7 NO YES YES 1BPI G37A 45.70 39.00 7.00 2.30 -0.62 Decrease 5 Decrease 7 NO YES YES 1BPI G36A 0.00 39.00 7.00 2.10 -0.87 Decrease 8 Decrease 9 NO YES YES 1LZ1 G37A 49.60 64.00 2.70 0.29 -0.18 Increase 4 Increase 5 NO NO NO 1BNI G53A 21.60 54.00 6.30 3.40 -0.56 Decrease 3 Decrease 4 NO YES YES 1BNI G52A 2.50 54.00 6.30 5.30 -1.27 Decrease 6 Decrease 5 NO YES YES 2LZM G113A 68.60 38.00 2.00 -0.50 -0.64 Increase 8 Increase 9 YES YES YES 2LZM G113A 68.60 41.00 2.00 -0.10 -0.64 Increase 9 Increase 8 YES YES YES 2LZM G113A 68.60 46.00 2.50 -0.54 -0.64 Increase 9 Increase 10 YES YES YES 2LZM G113A 68.60 46.00 2.50 -0.54 -0.64 Increase 9 Increase 10 YES YES YES 2LZM G113A 68.60 64.00 6.50 -0.30 -0.64 Increase 10 Increase 10 YES YES YES 2RN2 G77A 0.00 49.00 3.00 0.90 -2.00 Increase 0 Increase 8 NO NO NO 2RN2 G23A 0.00 50.00 3.00 -0.70 -1.54 Increase 4 Increase 4 YES YES YES 2RN2 G23A 0.00 52.00 5.50 -0.50 -1.54 Increase 5 Increase 4 YES YES YES 1BNI G34A 44.50 25.00 6.30 3.12 -0.27 Decrease 3 Increase 3 NO NO YES 1BVC G129A 33.00 82.00 9.60 -1.10 -0.95 Decrease 1 Decrease 1 YES NO NO 2LZM G30A 20.30 66.00 5.40 -0.10 -0.53 Decrease 3 Decrease 4 YES NO NO 2LZM G77A 3.80 41.00 2.00 0.40 -1.42 Decrease 6 Decrease 6 NO YES YES 2LZM G77A 3.80 64.00 6.50 -0.40 -1.42 Decrease 5 Decrease 5 YES NO NO 1BVC G23A 10.20 82.00 9.60 1.10 -1.09 Decrease 3 Decrease 2 NO YES YES 1SUP G169A 1.30 58.00 8.00 -0.30 -1.55 Decrease 5 Decrease 5 YES NO NO 1ROP D30Y 96.50 69.00 7.00 -0.20 -0.37 Increase 3 Increase 8 YES YES YES 1STN H46Y 23.10 40.00 5.40 -0.00 -2.07 Increase 4 Decrease 3 NO NO NO 1A23 H32Y 32.40 30.00 7.00 -6.80 0.61 Decrease 3 Decrease 4 NO NO NO 2LZM S44Y 59.70 51.00 3.00 -0.19 0.06 Increase 7 Increase 8 NO YES YES 4LYZ S91Y 0.00 74.00 6.40 3.07 -4.49 Decrease 6 Decrease 8 NO YES YES 1BNI A32Y 78.90 25.00 6.30 0.80 0.32 Decrease 3 Decrease 3 YES YES YES 1RN1 A21Y 51.70 0.00 2.50 0.39 0.24 Decrease 7 Decrease 6 YES YES YES 2RN2 A52Y 0.00 53.00 3.20 2.30 -4.94 Decrease 4 Decrease 4 NO YES YES 5CRO Y26D 80.50 45.00 7.00 -2.70 0.49 Increase 4 Increase 1 NO YES YES 3MBP Y283D 20.60 25.00 7.60 3.20 4.64 Decrease 8 Decrease 9 YES YES YES 2ABD Y31N 29.50 5.00 5.30 1.52 4.75 Decrease 7 Decrease 6 YES YES YES 2ABD Y28N 28.50 5.00 5.30 2.23 1.01 Decrease 7 Decrease 7 YES YES YES 5CRO Y26Q 80.50 45.00 7.00 -1.40 0.50 Increase 6 Decrease 0 NO NO YES 1SUP Y217K 32.30 58.00 8.00 -0.72 2.97 Increase 5 Increase 6 NO YES YES 1VQB Y26R 39.80 25.00 7.00 0.40 2.54 Decrease 0 Increase 5 YES NO YES 5CRO Y26H 80.50 45.00 7.00 -1.90 0.60 Decrease 0 Decrease 3 NO NO NO 5CRO Y26C 80.50 45.00 3.00 -2.20 0.40 Increase 6 Increase 8 NO YES YES 5CRO Y26C 80.50 45.00 3.00 -2.20 0.40 Increase 6 Increase 8 NO YES YES 1BNI Y17S 60.80 25.00 6.30 2.57 0.89 Decrease 8 Decrease 7 YES YES YES 1STN Y91S 0.00 20.00 7.00 5.30 7.31 Decrease 8 Decrease 6 YES YES YES 1BPI Y23A 5.10 25.00 2.00 5.90 4.05 Decrease 9 Decrease 9 YES YES YES 1BPI Y10A 41.60 39.00 7.00 1.20 1.29 Decrease 7 Decrease 8 YES YES YES 1BPI Y35A 8.90 39.00 7.00 1.10 2.08 Decrease 8 Decrease 9 YES YES YES 1BNI Y17A 60.80 25.00 6.30 2.00 2.18 Decrease 6 Decrease 5 YES YES YES 1VQB Y41A 88.90 25.00 7.00 0.40 -0.07 Decrease 5 Decrease 6 NO YES YES 1BNI Y13A 19.20 25.00 6.30 3.30 3.46 Decrease 9 Decrease 9 YES YES YES 2ABD Y28A 28.50 5.00 5.30 2.47 1.82 Decrease 6 Decrease 6 YES YES YES 1LZ1 Y38A 10.30 64.00 2.70 2.49 3.36 Decrease 8 Decrease 9 YES YES YES 2ABD Y73A 3.70 5.00 5.30 4.83 4.09 Decrease 7 Decrease 5 YES YES YES 1BPI Y35G 8.90 25.00 2.00 5.00 3.39 Decrease 9 Decrease 9 YES YES YES 1BPI Y35G 8.90 25.00 2.00 5.00 3.39 Decrease 9 Decrease 9 YES YES YES 1BNI Y17G 60.80 25.00 6.30 4.03 3.36 Decrease 8 Decrease 9 YES YES YES 1LZ1 Y38G 10.30 64.00 2.70 2.32 4.31 Decrease 9 Decrease 9 YES YES YES 1ROP D30W 96.50 69.00 7.00 0.40 -0.48 Increase 1 Increase 5 NO NO NO 2LZM S44W 59.70 51.00 3.00 -0.05 -19.78 Increase 8 Increase 10 YES YES YES 1BNI A32W 78.90 25.00 6.30 1.00 0.16 Decrease 2 Decrease 1 YES YES YES 1RN1 A21W 51.70 0.00 2.50 0.30 0.09 Decrease 5 Decrease 9 YES YES YES 1RN1 Y45W 84.70 25.00 6.00 -0.74 0.41 Increase 3 Increase 5 NO YES YES 5CRO Y26W 80.50 45.00 7.00 0.10 0.18 Increase 6 Increase 8 YES NO NO 1RN1 Y42W 3.30 25.00 6.00 0.14 -1.71 Decrease 6 Decrease 6 NO YES YES 1RN1 Y24W 19.70 25.00 6.00 -1.24 -1.26 Decrease 4 Decrease 8 YES NO NO 1BNI W94Y 27.00 25.00 5.80 1.27 1.30 Decrease 9 Decrease 9 YES YES YES 1BNI W94Y 27.00 25.00 9.00 0.99 1.30 Decrease 9 Decrease 9 YES YES YES 1RN1 W59Y 0.80 25.00 6.00 0.93 2.88 Decrease 9 Decrease 9 YES YES YES 1ROP D30F 96.50 69.00 7.00 0.10 -0.14 Increase 1 Decrease 0 NO YES NO 4LYZ D101F 72.20 74.00 6.40 -0.72 -0.20 Increase 10 Increase 9 YES YES YES 2LZM N132F 30.70 66.00 5.40 -1.30 -2.39 Increase 10 Increase 10 YES YES YES 1VQB E30F 28.60 25.00 7.00 -2.10 -2.59 Decrease 8 Decrease 8 YES NO NO 2LZM E11F 21.20 66.00 5.40 -1.70 -2.97 Increase 7 Increase 4 YES YES YES 2LZM T157F 35.30 42.00 2.00 2.40 1.75 Decrease 4 Decrease 3 YES YES YES 2LZM S44F 59.70 51.00 3.00 -0.06 -0.05 Increase 8 Increase 9 YES YES YES 2LZM S117F 1.70 51.00 3.00 -1.40 -5.70 Decrease 0 Decrease 2 YES NO NO 2LZM S117F 1.70 65.00 5.40 -1.10 -5.70 Increase 3 Decrease 1 YES NO YES 2LZM S117F 1.70 65.00 5.40 -1.10 -5.70 Increase 3 Decrease 1 YES NO YES 1BNI A32F 78.90 25.00 6.30 0.70 0.23 Decrease 2 Decrease 1 YES YES YES 1RN1 A21F 51.70 0.00 2.50 0.57 0.48 Decrease 5 Decrease 4 YES YES YES 2RN2 A52F 0.00 53.00 3.20 -0.50 -5.62 Decrease 3 Decrease 7 YES NO NO 2LZM G30F 20.30 66.00 5.40 1.50 -3.57 Decrease 3 Decrease 3 NO YES YES 1LZ1 Y45F 59.90 64.00 2.70 -0.07 -0.25 Increase 8 Increase 9 YES YES YES 1BNI Y103F 29.00 25.00 6.30 -0.00 1.64 Decrease 1 Decrease 5 NO NO NO 1LZ1 Y54F 10.30 64.00 2.70 0.96 0.78 Decrease 3 Increase 0 YES NO YES 1RTB Y97F 4.70 63.00 5.00 3.54 0.83 Decrease 7 Decrease 7 YES YES YES 5CRO Y26F 80.50 45.00 7.00 -0.40 -0.05 Increase 7 Increase 6 YES YES YES 1BNI Y17F 60.80 25.00 6.30 0.30 0.00 Decrease 4 Decrease 3 NO YES YES 1LZ1 Y63F 56.60 64.00 2.70 0.24 0.08 Decrease 6 Decrease 7 YES YES YES 1VQB Y41F 88.90 25.00 7.00 0.60 -0.01 Decrease 4 Decrease 5 NO YES YES 1RN1 Y68F 4.70 25.00 7.00 1.36 0.54 Decrease 2 Increase 6 YES NO YES 1RN1 Y68F 4.70 50.00 7.00 1.35 0.54 Increase 4 Increase 8 YES NO NO 1BNI Y13F 19.20 25.00 6.30 0.41 -0.24 Decrease 8 Decrease 8 NO YES YES 1BNI Y24F 7.50 25.00 6.30 -0.00 0.50 Decrease 9 Decrease 9 NO NO NO 1RN1 Y56F 11.70 25.00 7.00 0.78 0.67 Decrease 6 Decrease 7 YES YES YES 1RN1 Y56F 11.70 50.00 7.00 0.71 0.67 Decrease 3 Decrease 1 YES YES YES 1RN1 Y11F 1.90 25.00 7.00 2.11 0.12 Decrease 9 Decrease 9 YES YES YES 1RN1 Y11F 1.90 50.00 7.00 2.03 0.12 Decrease 9 Decrease 9 YES YES YES 1C9O Y15F 33.70 70.00 7.00 0.05 0.04 Increase 6 Increase 9 YES NO NO 1C9O Y15F 33.70 70.00 7.00 -0.07 0.04 Increase 6 Increase 3 NO YES YES 1LZ1 Y20F 25.30 64.00 2.70 0.50 0.40 Decrease 5 Decrease 5 YES YES YES 2ABD Y28F 28.50 5.00 5.30 1.06 -0.57 Decrease 4 Decrease 5 NO YES YES 1LZ1 Y124F 9.40 64.00 2.70 0.36 0.36 Decrease 8 Decrease 8 YES YES YES 1LZ1 Y38F 10.30 64.00 2.70 0.19 -0.29 Decrease 7 Decrease 8 NO YES YES 2ABD Y73F 3.70 5.00 5.30 -0.27 -0.50 Decrease 6 Decrease 8 YES NO NO 1RN1 Y42F 3.30 25.00 7.00 -1.14 0.20 Decrease 7 Decrease 5 NO NO NO 1RN1 Y42F 3.30 50.00 7.00 -1.15 0.20 Decrease 5 Decrease 7 NO NO NO 1BNI Y78F 3.70 25.00 6.30 1.40 1.74 Decrease 9 Decrease 9 YES YES YES 1RN1 Y57F 13.10 25.00 7.00 0.50 0.69 Decrease 6 Decrease 4 YES YES YES 1RN1 Y57F 13.10 50.00 7.00 0.44 0.69 Decrease 3 Decrease 4 YES YES YES 1BNI W94F 27.00 25.00 5.80 1.06 1.52 Decrease 9 Decrease 9 YES YES YES 1BNI W94F 27.00 25.00 9.00 0.60 1.52 Decrease 9 Decrease 9 YES YES YES 1BVC W7F 7.50 4.00 7.80 0.90 0.88 Decrease 7 Decrease 1 YES YES YES 1BVC W7F 7.50 4.00 7.80 -0.10 0.88 Decrease 7 Decrease 8 NO NO NO 1BVC W14F 2.50 4.00 7.80 1.10 1.67 Decrease 7 Decrease 9 YES YES YES 1BVC F123K 0.50 4.00 7.80 2.10 7.28 Decrease 9 Decrease 8 YES YES YES 1CYO F35H 11.50 66.00 7.00 2.82 2.69 Decrease 4 Decrease 4 YES YES YES 1VQB F13T 27.90 25.00 7.00 0.70 0.80 Decrease 8 Decrease 7 YES YES YES 1BPI F4A 8.00 39.00 7.00 3.00 3.00 Decrease 9 Decrease 9 YES YES YES 1CSP F38A 81.20 60.00 7.00 -0.31 -0.15 Increase 9 Increase 9 YES YES YES 1BPI F45A 9.50 25.00 2.00 6.90 3.57 Decrease 9 Decrease 9 YES YES YES 1BPI F22A 12.00 25.00 2.00 1.20 4.38 Decrease 9 Decrease 9 YES YES YES 1BPI F22A 12.00 39.00 7.00 2.00 4.38 Decrease 9 Decrease 9 YES YES YES 2LZM F67A 6.50 51.00 3.00 1.90 3.85 Decrease 8 Decrease 8 YES YES YES 1STN F76A 9.00 20.00 7.00 4.10 2.05 Decrease 8 Decrease 9 YES YES YES 1CSP F15A 25.90 60.00 7.00 1.67 2.15 Decrease 4 Decrease 3 YES YES YES 2ABD F5A 0.00 5.00 5.30 2.52 4.07 Decrease 9 Decrease 9 YES YES YES 1STN F61A 28.90 20.00 7.00 2.40 2.01 Decrease 9 Decrease 9 YES YES YES 2LZM F104A 16.40 51.00 3.00 3.10 1.72 Decrease 9 Decrease 9 YES YES YES 1CSP F27A 35.40 60.00 7.00 0.69 1.78 Decrease 6 Decrease 6 YES YES YES 1CSP F17A 29.90 60.00 7.00 1.34 2.66 Decrease 7 Decrease 8 YES YES YES 2LZM F153A 0.50 51.00 3.00 3.50 4.34 Decrease 9 Decrease 9 YES YES YES 2LZM F153A 0.50 64.00 5.70 3.80 4.34 Decrease 8 Decrease 9 YES YES YES 2LZM F153A 0.50 65.00 5.40 3.40 4.34 Decrease 8 Decrease 9 YES YES YES 2CI2 F69A 17.40 25.00 6.20 3.84 3.29 Decrease 9 Decrease 9 YES YES YES 1STN F76G 9.00 20.00 7.00 4.70 2.41 Decrease 8 Decrease 9 YES YES YES 1STN F61G 28.90 20.00 7.00 4.70 3.11 Decrease 9 Decrease 9 YES YES YES 1CYO F35Y 11.50 66.00 7.00 -0.79 1.15 Increase 1 Increase 1 NO YES YES 4LYZ F34Y 34.90 74.00 6.40 -0.19 0.03 Increase 2 Decrease 8 NO NO YES 4LYZ F3Y 9.00 74.00 6.40 0.45 -1.84 Decrease 5 Decrease 5 NO YES YES 1VQB F73W 88.20 25.00 7.00 -0.80 -0.02 Increase 3 Decrease 3 YES NO YES 1ROP D30M 96.50 69.00 7.00 -0.60 -0.66 Increase 7 Increase 4 YES YES YES 1BNI D22M 104.80 25.00 4.40 0.27 0.20 Decrease 1 Decrease 0 YES YES YES 2LZM N132M 30.70 66.00 5.40 -1.50 -0.21 Increase 9 Increase 8 YES YES YES 1VQB E30M 28.60 25.00 7.00 -0.70 -0.29 Decrease 9 Decrease 9 YES NO NO 2LZM E11M 21.20 66.00 5.40 -1.60 -0.29 Increase 5 Increase 3 YES YES YES 2LZM Q105M 31.90 59.00 5.40 1.20 -0.18 Decrease 2 Decrease 0 NO YES YES 2ABD K52M 35.00 5.00 5.30 -0.18 -0.51 Increase 2 Increase 1 YES YES YES 2ABD K54M 22.40 5.00 5.30 -0.27 0.35 Increase 2 Increase 0 NO YES YES 1VQB K69M 51.00 25.00 7.00 -0.20 0.45 Increase 4 Decrease 1 NO NO YES 2CI2 K21M 39.40 25.00 6.20 0.67 0.98 Decrease 5 Decrease 5 YES YES YES 1BNI R69M 16.60 25.00 4.40 2.86 -0.55 Decrease 8 Decrease 8 NO YES YES 1BNI R69M 16.60 25.00 6.30 2.12 -0.55 Decrease 7 Decrease 7 NO YES YES 2LZM R119M 49.80 40.00 2.00 0.30 -0.98 Decrease 4 Decrease 4 NO YES YES 2LZM R119M 49.80 66.00 5.70 -0.10 -0.98 Increase 6 Increase 6 YES YES YES 1VQB C33M 0.00 25.00 7.00 3.50 -2.08 Decrease 9 Decrease 9 NO YES YES 2LZM S44M 59.70 51.00 3.00 -0.33 0.16 Increase 8 Increase 7 NO YES YES 1BNI A32M 78.90 25.00 6.30 0.30 -0.07 Decrease 2 Increase 3 NO NO YES 1RN1 A21M 51.70 0.00 2.50 0.15 0.15 Decrease 8 Decrease 8 YES YES YES 2LZM A129M 0.00 65.00 5.40 1.90 -2.00 Decrease 4 Decrease 3 NO YES YES 2RN2 A52M 0.00 53.00 3.20 -0.50 -2.27 Decrease 4 Decrease 8 YES NO NO 2LZM F153M 0.50 51.00 3.00 0.80 2.34 Decrease 9 Decrease 8 YES YES YES 2LZM F153M 0.50 65.00 5.40 0.60 2.34 Decrease 9 Decrease 9 YES YES YES 2LZM F153M 0.50 65.00 5.40 0.60 2.34 Decrease 9 Decrease 9 YES YES YES 3SSI M73D 94.00 53.00 3.20 -1.08 -0.19 Decrease 4 Decrease 4 YES NO NO 3SSI M73D 94.00 53.00 7.00 -1.60 -0.19 Decrease 3 Decrease 3 YES NO NO 3SSI M73D 94.00 53.00 9.50 -1.25 -0.19 Decrease 3 Decrease 4 YES NO NO 3SSI M73E 94.00 53.00 3.20 -0.35 0.14 Decrease 4 Decrease 4 NO NO NO 3SSI M73E 94.00 53.00 7.00 -1.05 0.14 Decrease 3 Decrease 4 NO NO NO 3SSI M73E 94.00 53.00 9.50 -0.56 0.14 Decrease 3 Decrease 4 NO NO NO 3SSI M73K 94.00 53.00 3.20 -1.27 0.12 Decrease 6 Decrease 4 NO NO NO 3SSI M73K 94.00 53.00 7.00 -0.35 0.12 Decrease 5 Decrease 5 NO NO NO 3SSI M73K 94.00 53.00 9.50 -0.05 0.12 Decrease 5 Decrease 5 NO NO NO 2LZM M120K 15.00 47.00 3.00 1.60 0.20 Decrease 9 Decrease 9 YES YES YES 2LZM M106K 28.00 47.00 3.00 3.40 1.89 Decrease 7 Decrease 6 YES YES YES 2LZM M102K 1.50 47.00 10.40 2.20 2.03 Decrease 8 Decrease 7 YES YES YES 2LZM M102K 1.50 51.00 3.00 8.90 2.03 Decrease 9 Decrease 9 YES YES YES 2LZM M102K 1.50 65.00 5.30 6.90 2.03 Decrease 8 Decrease 6 YES YES YES 1VQB M77C 43.50 25.00 7.00 -0.00 0.50 Decrease 5 Decrease 8 NO NO NO 1VQB M77T 43.50 25.00 7.00 0.80 -0.27 Decrease 8 Decrease 8 NO YES YES 4LYZ M105T 0.00 20.00 9.50 0.24 3.05 Decrease 9 Decrease 9 YES YES YES 1BPI M52A 60.00 39.00 7.00 1.70 -0.10 Decrease 8 Decrease 8 NO YES YES 1VQB M77A 43.50 25.00 7.00 2.10 0.16 Decrease 7 Decrease 8 YES YES YES 3SSI M73A 94.00 53.00 3.20 -0.54 -0.11 Decrease 3 Decrease 3 YES NO NO 3SSI M73A 94.00 53.00 7.00 -0.55 -0.11 Decrease 3 Decrease 3 YES NO NO 3SSI M73A 94.00 53.00 9.50 -0.13 -0.11 Decrease 3 Decrease 2 YES NO NO 2LZM M120A 15.00 51.00 3.00 0.20 0.57 Decrease 8 Decrease 7 YES YES YES 2LZM M6A 0.00 51.00 3.00 1.90 2.26 Decrease 7 Decrease 6 YES YES YES 2LZM M106A 28.00 51.00 3.00 2.30 2.21 Decrease 3 Decrease 1 YES YES YES 1BVC M131A 0.00 4.00 7.80 2.20 2.21 Decrease 3 Decrease 3 YES YES YES 3SSI M103A 0.00 53.00 3.20 1.35 2.07 Decrease 8 Decrease 8 YES YES YES 3SSI M103A 0.00 80.00 9.50 2.80 14.61 Decrease 6 Decrease 4 YES YES YES 3SSI M103A 0.00 82.00 7.00 2.32 2.07 Decrease 7 Decrease 6 YES YES YES 3SSI M73G 94.00 53.00 3.20 0.21 -0.13 Decrease 7 Decrease 6 NO YES YES 3SSI M73G 94.00 53.00 7.00 0.06 -0.13 Decrease 6 Decrease 6 NO YES YES 3SSI M73G 94.00 53.00 9.50 0.49 -0.13 Decrease 6 Decrease 5 NO YES YES 3SSI M103G 0.00 80.00 9.50 7.10 3.65 Decrease 9 Decrease 9 YES YES YES 3SSI M103G 0.00 82.00 7.00 6.82 3.65 Decrease 9 Decrease 9 YES YES YES 1VQB M77F 43.50 25.00 7.00 0.20 -1.26 Decrease 4 Decrease 4 NO YES YES 1SUP M50F 16.50 58.00 8.00 -0.48 -2.34 Increase 7 Increase 8 YES YES YES 2RN2 D134I 37.50 50.00 3.00 -0.69 -0.51 Increase 9 Increase 10 YES YES YES 2RN2 D134I 37.50 53.00 5.50 -1.27 -0.51 Increase 9 Increase 9 YES YES YES 1ROP D30I 96.50 69.00 7.00 0.80 -0.12 Increase 3 Increase 6 NO NO NO 2LZM N132I 30.70 66.00 5.40 -1.20 -1.24 Increase 10 Increase 10 YES YES YES 1BNI Q15I 42.60 25.00 6.30 -1.00 0.40 Decrease 4 Decrease 8 NO NO NO 1VQB C33I 0.00 25.00 7.00 0.90 -2.67 Decrease 8 Decrease 9 NO YES YES 2LZM T157I 35.30 62.00 4.00 2.10 1.63 Decrease 0 Increase 1 YES NO YES 2LZM T157I 35.30 42.00 2.00 2.90 1.63 Decrease 2 Decrease 1 YES YES YES 2LZM T157I 35.30 46.00 2.50 1.90 1.63 Decrease 2 Decrease 2 YES YES YES 2LZM T157I 35.30 53.00 3.00 1.50 1.63 Decrease 1 Decrease 0 YES YES YES 2LZM T157I 35.30 62.00 4.00 2.10 1.63 Decrease 0 Increase 1 YES NO YES 2LZM T157I 35.30 64.00 6.00 1.20 1.63 Decrease 0 Increase 2 YES NO YES 3MBP T345I 36.80 25.00 7.60 -0.70 -0.04 Decrease 2 Decrease 0 YES NO NO 1HFY T33I 21.60 20.00 2.00 -0.18 -2.27 Decrease 3 Decrease 3 YES NO NO 4LYZ T40I 0.70 74.00 6.40 2.20 -0.67 Decrease 2 Decrease 2 NO YES YES 2LZM T152I 0.00 59.00 5.40 0.40 -2.41 Decrease 1 Increase 5 NO NO YES 1HFY T29I 0.00 20.00 2.00 -0.12 -2.56 Decrease 4 Decrease 4 YES NO NO 2LZM S44I 59.70 51.00 3.00 -0.31 -0.11 Increase 9 Increase 9 YES YES YES 2LZM S117I 1.70 66.00 5.40 -1.70 -3.09 Increase 6 Increase 9 YES YES YES 1BNI A32I 78.90 25.00 6.30 0.80 -0.15 Increase 1 Increase 0 NO NO NO 1HFY A30I 0.00 20.00 2.00 -0.30 -3.43 Decrease 5 Decrease 9 YES NO NO 1RN1 A21I 51.70 0.00 2.50 0.44 0.06 Decrease 4 Decrease 3 YES YES YES 4LYZ A31I 0.00 74.00 6.40 -1.40 -2.81 Increase 9 Increase 9 YES YES YES 2RN2 A52I 0.00 53.00 3.20 -1.90 -2.83 Decrease 1 Decrease 2 YES NO NO 2LZM F153I 0.50 51.00 3.00 0.50 1.42 Decrease 7 Decrease 7 YES YES YES 2LZM F153I 0.50 64.00 5.70 0.20 1.42 Decrease 6 Decrease 4 YES YES YES 1VQB M77I 43.50 25.00 7.00 -1.60 -0.52 Decrease 2 Decrease 2 YES NO NO 3SSI M73I 94.00 53.00 3.20 0.73 0.26 Decrease 2 Decrease 4 YES YES YES 3SSI M73I 94.00 53.00 7.00 0.94 0.26 Decrease 2 Decrease 3 YES YES YES 3SSI M73I 94.00 53.00 9.50 1.28 0.26 Decrease 2 Decrease 2 YES YES YES 2LZM M6I 0.00 65.00 6.00 1.38 -1.11 Decrease 3 Decrease 4 NO YES YES 3SSI M103I 0.00 53.00 3.20 2.01 -1.04 Decrease 6 Decrease 4 NO YES YES 3SSI M103I 0.00 80.00 9.50 2.29 -1.04 Decrease 4 Decrease 3 NO YES YES 3SSI M103I 0.00 82.00 7.00 1.89 -1.04 Decrease 4 Decrease 4 NO YES YES 2LZM I3D 11.90 41.00 2.00 1.80 3.27 Decrease 9 Decrease 9 YES YES YES 2LZM I3D 11.90 64.00 6.50 3.20 3.27 Decrease 9 Decrease 9 YES YES YES 2LZM I3E 11.90 38.00 2.00 1.77 2.33 Decrease 9 Decrease 9 YES YES YES 2LZM I3E 11.90 41.00 2.00 1.10 2.33 Decrease 9 Decrease 9 YES YES YES 2LZM I3E 11.90 46.00 2.50 1.71 2.33 Decrease 9 Decrease 9 YES YES YES 2LZM I3E 11.90 53.00 3.00 1.53 2.33 Decrease 9 Decrease 9 YES YES YES 2LZM I3E 11.90 64.00 6.50 2.00 2.33 Decrease 9 Decrease 9 YES YES YES 1VQB I78C 50.80 25.00 7.00 4.40 0.45 Decrease 9 Decrease 8 YES YES YES 1VQB I47C 2.20 25.00 7.00 5.30 2.42 Decrease 9 Decrease 9 YES YES YES 1BNI I55T 46.50 25.00 6.30 0.60 0.18 Decrease 8 Decrease 7 YES YES YES 2LZM I58T 3.80 59.00 5.40 3.40 1.86 Decrease 8 Decrease 8 YES YES YES 1LZ1 I56T 1.60 64.00 2.70 3.64 3.30 Decrease 8 Decrease 9 YES YES YES 4LYZ I55T 2.20 74.00 6.40 4.96 1.42 Decrease 8 Decrease 8 YES YES YES 1VQB I78T 50.80 25.00 7.00 6.60 0.52 Decrease 9 Decrease 9 YES YES YES 2CI2 I49T 38.40 25.00 6.30 1.34 1.04 Decrease 9 Decrease 9 YES YES YES 2LZM I3T 11.90 38.00 2.00 2.45 2.58 Decrease 9 Decrease 9 YES YES YES 2LZM I3T 11.90 41.00 2.00 1.70 2.58 Decrease 9 Decrease 9 YES YES YES 2LZM I3T 11.90 46.00 2.50 2.28 2.58 Decrease 9 Decrease 9 YES YES YES 2LZM I3T 11.90 53.00 3.00 1.81 2.58 Decrease 9 Decrease 9 YES YES YES 2LZM I3T 11.90 64.00 6.50 2.30 2.58 Decrease 9 Decrease 9 YES YES YES 1VQB I47T 2.20 25.00 7.00 7.40 2.30 Decrease 9 Decrease 9 YES YES YES 2LZM I3S 11.90 41.00 2.00 1.90 3.45 Decrease 9 Decrease 9 YES YES YES 2LZM I3S 11.90 64.00 6.50 1.70 3.45 Decrease 9 Decrease 9 YES YES YES 2LZM I3P 11.90 38.00 2.00 2.96 0.73 Decrease 9 Decrease 9 YES YES YES 2LZM I3P 11.90 46.00 2.50 2.97 0.73 Decrease 9 Decrease 9 YES YES YES 2LZM I3P 11.90 53.00 3.00 2.53 0.73 Decrease 9 Decrease 9 YES YES YES 1BNI I55A 46.50 25.00 6.30 1.10 0.49 Decrease 9 Decrease 9 YES YES YES 1BVC I142A 1.10 76.00 11.00 1.10 2.55 Decrease 2 Decrease 3 YES YES YES 1BVC I142A 1.10 82.00 9.60 1.90 2.55 Decrease 0 Decrease 0 YES YES YES 1BPI I18A 32.40 39.00 7.00 1.50 1.24 Decrease 9 Decrease 9 YES YES YES 1BPI I19A 55.70 39.00 7.00 2.10 0.96 Decrease 9 Decrease 9 YES YES YES 1BNI I25A 8.60 25.00 6.30 3.50 2.88 Decrease 9 Decrease 9 YES YES YES 1BNI I109A 23.20 25.00 6.30 2.10 2.34 Decrease 9 Decrease 9 YES YES YES 1BNI I76A 0.00 25.00 6.30 1.90 3.40 Decrease 9 Decrease 9 YES YES YES 2LZM I50A 20.50 51.00 3.00 2.00 2.39 Decrease 9 Decrease 9 YES YES YES 2LZM I17A 12.40 51.00 3.00 2.70 2.33 Decrease 9 Decrease 9 YES YES YES 1BNI I96A 0.00 25.00 6.30 3.20 4.56 Decrease 9 Decrease 9 YES YES YES 1BNI I96A 0.00 25.00 6.30 3.20 4.56 Decrease 9 Decrease 9 YES YES YES 2LZM I58A 3.80 51.00 3.00 3.20 3.46 Decrease 9 Decrease 9 YES YES YES 2LZM I29A 2.20 51.00 3.00 2.60 2.86 Decrease 9 Decrease 9 YES YES YES 1BNI I88A 0.00 25.00 6.30 4.00 3.53 Decrease 9 Decrease 9 YES YES YES 1BNI I88A 0.00 48.00 6.30 3.90 3.53 Decrease 9 Decrease 9 YES YES YES 2LZM I27A 0.00 51.00 3.00 3.10 2.70 Decrease 9 Decrease 9 YES YES YES 2CI2 I56A 88.10 25.00 6.20 0.03 -0.11 Decrease 7 Decrease 7 NO YES YES 1BNI I4A 30.30 25.00 6.30 1.40 1.35 Decrease 9 Decrease 9 YES YES YES 1LZ1 I89A 3.80 64.00 2.70 2.70 2.25 Decrease 9 Decrease 9 YES YES YES 1LZ1 I56A 1.60 64.00 2.70 3.71 3.46 Decrease 9 Decrease 9 YES YES YES 1LZ1 I106A 2.70 64.00 2.70 0.93 3.80 Decrease 9 Decrease 9 YES YES YES 1LZ1 I23A 8.10 64.00 2.70 2.54 3.46 Decrease 8 Decrease 9 YES YES YES 1BNI I51A 0.00 25.00 6.30 4.70 2.76 Decrease 9 Decrease 9 YES YES YES 1LZ1 I59A 1.60 64.00 2.70 1.72 3.13 Decrease 9 Decrease 9 YES YES YES 4LYZ I55A 2.20 74.00 6.40 4.40 2.47 Decrease 8 Decrease 9 YES YES YES 2CI2 I49A 38.40 25.00 6.30 2.12 1.27 Decrease 9 Decrease 8 YES YES YES 2CI2 I49A 38.40 25.00 6.30 2.12 1.27 Decrease 9 Decrease 8 YES YES YES 2LZM I3A 11.90 41.00 2.00 1.10 2.50 Decrease 9 Decrease 9 YES YES YES 2LZM I3A 11.90 64.00 6.50 0.70 2.50 Decrease 9 Decrease 9 YES YES YES 2LZM I78A 0.00 51.00 3.00 1.60 3.45 Decrease 9 Decrease 9 YES YES YES 2CI2 I48A 21.60 25.00 3.50 3.89 2.96 Decrease 9 Decrease 9 YES YES YES 2CI2 I48A 21.60 25.00 6.30 3.84 2.96 Decrease 9 Decrease 9 YES YES YES 1VQB I47A 2.20 25.00 7.00 7.00 2.78 Decrease 9 Decrease 9 YES YES YES 1BVC I28A 2.70 76.00 11.00 1.30 2.92 Decrease 4 Decrease 4 YES YES YES 1BVC I111A 2.70 76.00 11.00 1.80 2.83 Decrease 5 Decrease 7 YES YES YES 2LZM I100A 4.90 51.00 3.00 3.40 2.75 Decrease 9 Decrease 9 YES YES YES 2CI2 I76A 1.10 25.00 3.00 4.23 3.84 Decrease 9 Decrease 9 YES YES YES 2CI2 I76A 1.10 25.00 3.50 4.34 3.84 Decrease 9 Decrease 9 YES YES YES 2CI2 I76A 1.10 25.00 6.30 4.25 3.84 Decrease 9 Decrease 9 YES YES YES 1STN I18G 22.20 20.00 7.00 2.60 2.40 Decrease 9 Decrease 8 YES YES YES 1LZ1 I59G 1.60 64.00 2.70 3.83 4.32 Decrease 9 Decrease 9 YES YES YES 2CI2 I49G 38.40 25.00 6.30 3.52 2.19 Decrease 9 Decrease 9 YES YES YES 2LZM I3G 11.90 41.00 2.00 1.80 4.16 Decrease 9 Decrease 9 YES YES YES 2LZM I3G 11.90 64.00 6.50 2.10 4.16 Decrease 9 Decrease 9 YES YES YES 2LZM I3Y 11.90 41.00 2.00 2.70 -1.39 Decrease 9 Decrease 9 NO YES YES 2LZM I3Y 11.90 64.00 6.50 2.30 -1.39 Decrease 9 Decrease 9 NO YES YES 2LZM I3W 11.90 64.00 6.50 2.80 -2.24 Decrease 8 Decrease 7 NO YES YES 4LYZ I55F 2.20 74.00 6.40 2.46 -1.85 Decrease 7 Decrease 7 NO YES YES 2AKY I213F 0.00 25.00 7.50 1.91 -1.87 Decrease 9 Decrease 9 NO YES YES 2LZM I3F 11.90 38.00 2.00 1.49 -2.37 Decrease 9 Decrease 9 NO YES YES 2LZM I3F 11.90 41.00 2.00 1.00 -2.37 Decrease 9 Decrease 9 NO YES YES 2LZM I3F 11.90 46.00 2.50 1.09 -2.37 Decrease 9 Decrease 9 NO YES YES 2LZM I3F 11.90 53.00 3.00 0.53 -2.37 Decrease 9 Decrease 9 NO YES YES 2LZM I3F 11.90 64.00 6.50 1.10 -2.37 Decrease 8 Decrease 9 NO YES YES 1VQB I47F 2.20 25.00 7.00 2.00 -1.50 Decrease 9 Decrease 9 NO YES YES 1BVC I142M 1.10 76.00 11.00 -0.90 0.23 Increase 4 Increase 4 NO YES YES 1STN I18M 22.20 40.00 5.40 0.20 1.45 Decrease 8 Decrease 6 YES YES YES 4LYZ I55M 2.20 74.00 6.40 2.27 0.85 Decrease 8 Decrease 8 YES YES YES 2LZM I3M 11.90 41.00 2.00 0.30 0.39 Decrease 9 Decrease 9 YES YES YES 2LZM I3M 11.90 64.00 6.50 0.90 0.39 Decrease 9 Decrease 9 YES YES YES 2LZM I78M 0.00 65.00 5.40 1.50 0.93 Decrease 9 Decrease 9 YES YES YES 1VQB I47M 2.20 25.00 7.00 2.20 0.78 Decrease 9 Decrease 9 YES YES YES 1BVC I28M 2.70 76.00 11.00 0.60 0.44 Decrease 4 Decrease 5 YES YES YES 1BVC I111M 2.70 76.00 11.00 1.10 0.80 Decrease 6 Decrease 6 YES YES YES 2LZM I100M 4.90 65.00 5.40 1.60 1.02 Decrease 9 Decrease 9 YES YES YES 2RN2 D134L 37.50 50.00 3.00 -1.15 -0.04 Increase 9 Increase 9 YES YES YES 2RN2 D134L 37.50 53.00 5.50 -1.51 -0.04 Increase 9 Increase 8 YES YES YES 1ROP D30L 96.50 69.00 7.00 0.10 -0.16 Increase 1 Increase 4 NO NO NO 1CSP E66L 25.20 70.00 7.00 -2.11 -1.34 Increase 9 Increase 10 YES YES YES 1CSP E3L 42.40 70.00 7.00 -1.60 -2.80 Increase 2 Increase 4 YES YES YES 2RN2 Q80L 61.00 50.00 3.00 -0.30 0.38 Increase 8 Increase 6 NO YES YES 2RN2 Q76L 33.60 50.00 3.00 -0.24 0.01 Increase 7 Increase 7 NO YES YES 5CRO Q16L 26.90 45.00 3.00 -2.80 -1.87 Increase 8 Increase 9 YES YES YES 1C9O Q2L 41.40 70.00 7.00 -0.55 -1.23 Decrease 1 Decrease 2 YES NO NO 1C9O R3L 71.60 70.00 7.00 0.93 -0.90 Decrease 0 Increase 1 NO NO YES 4LYZ H15L 19.80 74.00 6.40 -0.76 -0.24 Increase 9 Increase 6 YES YES YES 1STN H124L 52.20 40.00 5.20 -0.70 -0.43 Increase 3 Decrease 0 YES NO YES 1STN H124L 52.20 47.00 5.00 -1.90 -0.43 Increase 4 Increase 5 YES YES YES 1STN H124L 52.20 51.00 7.00 -1.30 -0.43 Increase 5 Increase 1 YES YES YES 1VQB C33L 0.00 25.00 7.00 2.60 -2.49 Decrease 4 Decrease 4 NO YES YES 2LZM T157L 35.30 46.00 2.50 1.70 2.10 Decrease 1 Increase 1 YES NO YES 2LZM T157L 35.30 42.00 2.00 1.30 2.10 Decrease 1 Decrease 1 YES YES YES 2LZM T157L 35.30 46.00 2.50 1.70 2.10 Decrease 1 Increase 1 YES NO YES 2LZM T157L 35.30 46.00 2.50 1.70 2.10 Decrease 1 Increase 1 YES NO YES 1IOB T9L 4.30 25.00 6.50 0.70 -1.31 Decrease 3 Decrease 3 NO YES YES 2LZM S44L 59.70 51.00 3.00 -0.39 0.11 Increase 9 Increase 8 NO YES YES 2RN2 S68L 1.70 49.00 3.00 0.50 -2.93 Decrease 2 Decrease 2 NO YES YES 1ARR P8L 80.30 20.00 7.50 -2.40 1.32 Increase 8 Increase 8 NO YES YES 1ARR P8L 80.30 25.00 7.50 -2.49 1.32 Increase 8 Increase 8 NO YES YES 1ARR P8L 80.30 53.00 7.50 -2.55 1.32 Increase 10 Increase 9 NO YES YES 1BNI A32L 78.90 25.00 6.30 0.30 -0.05 Increase 1 Decrease 0 NO YES NO 1RN1 A21L 51.70 0.00 2.50 0.13 0.11 Decrease 1 Decrease 2 YES YES YES 2LZM A129L 0.00 65.00 5.40 1.30 -3.12 Increase 6 Increase 10 NO NO NO 4LYZ A31L 0.00 74.00 6.40 -1.80 -3.07 Increase 9 Increase 10 YES YES YES 1BVC A130L 0.00 4.00 7.80 0.90 -2.36 Decrease 1 Decrease 2 NO YES YES 1BVC A130L 0.00 4.00 7.80 -0.10 -2.36 Decrease 1 Decrease 1 YES NO NO 2RN2 A52L 0.00 53.00 3.20 -1.30 -3.09 Decrease 0 Decrease 2 YES NO NO 5CRO Y26L 80.50 45.00 7.00 -1.10 0.37 Increase 8 Increase 4 NO YES YES 1BNI W94L 27.00 25.00 5.80 1.59 2.09 Decrease 4 Decrease 3 YES YES YES 1BNI W94L 27.00 25.00 8.90 0.64 2.09 Decrease 3 Decrease 3 YES YES YES 1BNI W94L 27.00 25.00 9.00 0.66 2.09 Decrease 3 Decrease 4 YES YES YES 1CYO F35L 11.50 66.00 7.00 1.87 1.07 Increase 2 Increase 6 YES NO NO 1BNI F7L 13.00 25.00 6.20 4.60 1.05 Decrease 6 Decrease 6 YES YES YES 1VQB F68L 36.40 25.00 7.00 4.20 0.70 Decrease 1 Decrease 1 YES YES YES 1ANK F86L 2.50 51.00 7.20 0.80 2.40 Decrease 3 Decrease 7 YES YES YES 2LZM F153L 0.50 51.00 3.00 -0.20 1.62 Decrease 1 Decrease 2 NO NO NO 2LZM F153L 0.50 64.00 5.70 -0.30 1.62 Decrease 0 Decrease 3 NO NO NO 2LZM F153L 0.50 65.00 5.40 -0.35 1.62 Decrease 0 Decrease 0 NO NO NO 2CI2 F69L 17.40 25.00 6.20 2.11 0.72 Decrease 4 Decrease 4 YES YES YES 2CI2 F69L 17.40 25.00 6.20 2.11 0.72 Decrease 4 Decrease 4 YES YES YES 1VQB M77L 43.50 25.00 7.00 1.20 0.49 Decrease 1 Decrease 0 YES YES YES 3SSI M73L 94.00 53.00 3.20 0.13 0.17 Decrease 2 Decrease 2 YES YES YES 3SSI M73L 94.00 53.00 7.00 0.25 0.17 Decrease 2 Decrease 2 YES YES YES 3SSI M73L 94.00 53.00 9.50 0.55 0.17 Decrease 2 Decrease 2 YES YES YES 2LZM M120L 15.00 47.00 3.00 -0.50 -1.13 Decrease 1 Decrease 2 YES NO NO 2LZM M6L 0.00 47.00 3.00 2.80 -1.73 Decrease 2 Decrease 1 NO YES YES 2LZM M106L 28.00 47.00 3.00 -0.50 -0.12 Increase 0 Increase 1 YES YES YES 2LZM M102L 1.50 51.00 3.00 0.74 -0.70 Decrease 1 Decrease 0 NO YES YES 2LZM M102L 1.50 64.00 5.70 0.82 -0.70 Decrease 1 Decrease 2 NO YES YES 3SSI M103L 0.00 53.00 3.20 -0.77 -1.41 Decrease 2 Decrease 3 YES NO NO 3SSI M103L 0.00 80.00 9.50 0.29 -1.41 Decrease 2 Decrease 4 NO YES YES 3SSI M103L 0.00 82.00 7.00 -0.15 -1.41 Decrease 2 Decrease 2 YES NO NO 1BVC I142L 1.10 76.00 11.00 -0.60 -0.41 Increase 4 Increase 5 YES YES YES 1BNI I88L 0.00 25.00 6.30 0.30 -0.02 Decrease 7 Decrease 8 NO YES YES 4LYZ I55L 2.20 74.00 6.40 0.45 -0.44 Increase 4 Increase 6 NO NO NO 2LZM I3L 11.90 38.00 2.00 -0.85 0.04 Decrease 3 Decrease 4 NO NO NO 2LZM I3L 11.90 41.00 2.00 -0.90 0.04 Decrease 3 Decrease 4 NO NO NO 2LZM I3L 11.90 46.00 2.50 -1.01 0.04 Decrease 3 Increase 3 NO YES NO 2LZM I3L 11.90 53.00 3.00 -1.16 0.04 Decrease 2 Increase 4 NO YES NO 2LZM I3L 11.90 64.00 6.50 -0.40 0.04 Decrease 2 Decrease 3 NO NO NO 2LZM I3L 11.90 66.00 5.40 -0.70 0.04 Decrease 2 Decrease 4 NO NO NO 1VQB I47L 2.20 25.00 7.00 0.70 0.13 Decrease 6 Decrease 6 YES YES YES 1BVC I28L 2.70 76.00 11.00 0.60 0.07 Decrease 2 Decrease 0 YES YES YES 1BVC I111L 2.70 76.00 11.00 0.60 0.30 Decrease 2 Decrease 2 YES YES YES 2LZM L133D 0.50 51.00 3.00 4.90 2.76 Decrease 8 Decrease 7 YES YES YES 2LZM L133D 0.50 61.00 6.50 5.70 2.76 Decrease 8 Decrease 9 YES YES YES 2LZM L133D 0.50 64.00 4.40 5.50 2.76 Decrease 8 Decrease 7 YES YES YES 1C9O L66E 59.50 70.00 7.00 1.24 2.64 Decrease 9 Decrease 9 YES YES YES 1BNI L33Q 50.80 25.00 6.30 1.30 -0.15 Decrease 9 Decrease 9 NO YES YES 2TRX L78K 0.50 85.00 7.00 3.90 3.13 Decrease 9 Decrease 9 YES YES YES 1DDR L28R 59.50 15.00 7.80 -0.50 0.60 Decrease 9 Decrease 9 NO NO NO 1VQB L32R 41.50 25.00 7.00 1.60 0.59 Decrease 9 Decrease 9 YES YES YES 2TRX L78R 0.50 85.00 7.00 4.00 -12.18 Decrease 9 Decrease 9 NO YES YES 1VQB L32H 41.50 25.00 7.00 0.90 0.61 Decrease 9 Decrease 9 YES YES YES 1VQB L49C 3.30 25.00 7.00 4.10 2.56 Decrease 9 Decrease 9 YES YES YES 1VQB L37C 60.10 25.00 7.00 4.60 -0.03 Decrease 9 Decrease 9 NO YES YES 1VQB L81C 14.70 25.00 7.00 3.70 1.09 Decrease 9 Decrease 9 YES YES YES 1VQB L49T 3.30 25.00 7.00 5.70 3.07 Decrease 9 Decrease 8 YES YES YES 1BNI L89T 0.00 25.00 6.30 2.50 3.52 Decrease 9 Decrease 9 YES YES YES 1VQB L37T 60.10 25.00 7.00 5.20 0.31 Decrease 9 Decrease 9 YES YES YES 1VQB L81T 14.70 25.00 7.00 5.10 1.16 Decrease 9 Decrease 9 YES YES YES 1VQB L65P 77.00 25.00 7.00 1.50 -1.45 Decrease 9 Decrease 9 NO YES YES 1BPI L6A 56.80 39.00 7.00 0.60 0.61 Decrease 9 Decrease 9 YES YES YES 1BPI L29A 53.50 39.00 7.00 -0.00 0.02 Decrease 9 Decrease 9 NO NO NO 1BVC L149A 42.60 82.00 9.60 1.60 1.01 Decrease 8 Decrease 9 YES YES YES 1VQB L49A 3.30 25.00 7.00 6.10 2.88 Decrease 9 Decrease 9 YES YES YES 1ROP L41A 45.30 25.00 6.00 6.12 0.28 Decrease 9 Decrease 9 YES YES YES 2LZM L39A 39.90 53.00 5.50 0.90 0.50 Decrease 9 Decrease 9 YES YES YES 2ABD L25A 8.70 5.00 5.30 1.02 2.12 Decrease 9 Decrease 9 YES YES YES 1BNI L14A 0.00 25.00 6.30 4.30 3.27 Decrease 9 Decrease 9 YES YES YES 1BNI L14A 0.00 48.00 6.30 4.20 3.27 Decrease 9 Decrease 9 YES YES YES 2LZM L66A 1.60 51.00 3.00 3.90 1.86 Decrease 9 Decrease 9 YES YES YES 2LZM L46A 0.00 51.00 3.00 2.70 2.80 Decrease 9 Decrease 9 YES YES YES 2LZM L46A 0.00 53.00 5.50 2.10 2.80 Decrease 9 Decrease 9 YES YES YES 2LZM L46A 0.00 62.00 6.70 1.86 2.80 Decrease 9 Decrease 7 YES YES YES 2LZM L33A 8.20 51.00 3.00 3.60 3.18 Decrease 9 Decrease 9 YES YES YES 1BVC L137A 20.20 82.00 9.60 1.80 0.63 Decrease 7 Decrease 8 YES YES YES 2ABD L15A 0.50 5.00 5.30 3.10 3.11 Decrease 9 Decrease 9 YES YES YES 2ABD L80A 2.20 5.00 5.30 3.70 2.73 Decrease 9 Decrease 9 YES YES YES 2LZM L91A 3.30 51.00 3.00 3.10 3.03 Decrease 9 Decrease 9 YES YES YES 2CI2 L40A 42.10 25.00 6.20 1.33 0.94 Decrease 9 Decrease 9 YES YES YES 2LZM L133A 0.50 40.00 2.00 4.19 2.67 Decrease 9 Decrease 8 YES YES YES 2LZM L133A 0.50 51.00 3.00 4.30 2.67 Decrease 9 Decrease 8 YES YES YES 1BVC L9A 35.50 82.00 9.60 0.40 0.95 Decrease 8 Decrease 8 YES YES YES 2LZM L118A 6.60 51.00 3.00 3.50 2.33 Decrease 9 Decrease 9 YES YES YES 1BVC L11A 18.60 82.00 9.60 0.40 2.12 Decrease 8 Decrease 8 YES YES YES 1STN L25A 0.00 47.00 5.00 2.80 3.36 Decrease 9 Decrease 9 YES YES YES 1STN L25A 0.00 51.00 7.00 2.60 3.36 Decrease 9 Decrease 9 YES YES YES 2LZM L7A 0.00 51.00 3.00 2.60 3.25 Decrease 9 Decrease 9 YES YES YES 2LZM L121A 1.10 51.00 3.00 2.70 2.73 Decrease 9 Decrease 9 YES YES YES 2LZM L121A 1.10 65.00 5.40 2.30 2.73 Decrease 9 Decrease 9 YES YES YES 2LZM L84A 0.00 51.00 3.00 3.90 3.28 Decrease 9 Decrease 9 YES YES YES 1BVC L29A 1.60 76.00 11.00 2.40 2.72 Decrease 9 Decrease 9 YES YES YES 1VQB L37A 60.10 25.00 7.00 7.70 0.41 Decrease 9 Decrease 9 YES YES YES 1BVC L69A 2.20 76.00 11.00 1.20 2.89 Decrease 9 Decrease 9 YES YES YES 1STN L37A 7.60 20.00 7.00 1.80 2.88 Decrease 9 Decrease 9 YES YES YES 2CI2 L51A 20.80 25.00 6.20 2.37 1.93 Decrease 9 Decrease 9 YES YES YES 2CI2 L51A 20.80 25.00 6.20 2.37 1.93 Decrease 9 Decrease 9 YES YES YES 2CI2 L27A 1.10 25.00 3.00 2.66 3.18 Decrease 9 Decrease 9 YES YES YES 2CI2 L27A 1.10 25.00 6.30 2.64 3.18 Decrease 9 Decrease 9 YES YES YES 2CI2 L27A 1.10 46.00 6.30 2.68 3.18 Decrease 9 Decrease 9 YES YES YES 1STN L103A 0.00 20.00 7.00 4.60 2.94 Decrease 9 Decrease 9 YES YES YES 2LZM L99A 0.00 51.00 3.00 5.00 2.63 Decrease 9 Decrease 9 YES YES YES 2LZM L99A 0.00 64.00 5.70 4.50 2.63 Decrease 9 Decrease 9 YES YES YES 1STN L36A 0.50 20.00 7.00 3.60 3.05 Decrease 9 Decrease 9 YES YES YES 2CI2 L68A 0.00 25.00 3.50 3.74 3.17 Decrease 9 Decrease 9 YES YES YES 2CI2 L68A 0.00 25.00 6.30 3.82 3.17 Decrease 9 Decrease 9 YES YES YES 2CI2 L40G 42.10 25.00 6.20 1.38 1.85 Decrease 9 Decrease 9 YES YES YES 1STN L37G 7.60 20.00 7.00 3.90 4.23 Decrease 9 Decrease 9 YES YES YES 1STN L36G 0.50 20.00 7.00 5.40 4.25 Decrease 9 Decrease 9 YES YES YES 1VQB L32Y 41.50 25.00 7.00 -1.00 -3.13 Decrease 9 Decrease 9 YES NO NO 1VQB L32W 41.50 25.00 7.00 -2.80 -1.31 Decrease 9 Decrease 9 YES NO NO 1STN L89F 14.70 40.00 5.40 1.20 -0.64 Decrease 9 Decrease 9 NO YES YES 2LZM L133F 0.50 41.00 2.00 0.20 -2.63 Decrease 9 Decrease 9 NO YES YES 2LZM L133F 0.50 52.00 2.90 0.30 -2.63 Decrease 8 Decrease 9 NO YES YES 2LZM L99F 0.00 51.00 3.00 0.40 -1.32 Decrease 9 Decrease 9 NO YES YES 2LZM L99F 0.00 64.00 5.70 0.30 -1.32 Decrease 9 Decrease 9 NO YES YES 2LZM L91M 3.30 65.00 5.40 0.80 0.43 Decrease 9 Decrease 9 YES YES YES 1BVC L135M 0.50 76.00 11.00 0.80 0.64 Decrease 9 Decrease 9 YES YES YES 2LZM L133M 0.50 65.00 5.40 0.40 0.46 Decrease 8 Decrease 8 YES YES YES 2LZM L118M 6.60 65.00 5.40 0.70 0.87 Decrease 8 Decrease 8 YES YES YES 2LZM L121M 1.10 65.00 5.40 0.80 0.53 Decrease 9 Decrease 9 YES YES YES 2LZM L84M 0.00 65.00 5.40 1.90 1.01 Decrease 9 Decrease 9 YES YES YES 1BVC L29M 1.60 76.00 11.00 -0.10 1.01 Decrease 9 Decrease 9 NO NO NO 1BVC L69M 2.20 76.00 11.00 -0.00 0.50 Decrease 9 Decrease 9 NO NO NO 2LZM L99M 0.00 51.00 3.00 0.70 0.41 Decrease 9 Decrease 9 YES YES YES 2LZM L99M 0.00 64.00 5.70 0.60 0.41 Decrease 9 Decrease 9 YES YES YES 2LZM L99M 0.00 65.00 5.40 0.40 0.41 Decrease 9 Decrease 9 YES YES YES 1BVC L49I 18.60 76.00 11.00 0.80 -0.11 Decrease 2 Decrease 6 NO YES YES 1VQB L49I 3.30 25.00 7.00 1.90 0.98 Decrease 9 Decrease 9 YES YES YES 1BVC L135I 0.50 76.00 11.00 1.50 0.28 Decrease 7 Decrease 4 YES YES YES 1BVC L29I 1.60 76.00 11.00 1.10 0.08 Decrease 9 Decrease 9 YES YES YES 1VQB L37I 60.10 25.00 7.00 1.40 -0.28 Decrease 9 Decrease 9 NO YES YES 1BVC L69I 2.20 76.00 11.00 -0.00 0.05 Decrease 9 Decrease 9 NO NO NO 2CI2 L51I 20.80 25.00 6.20 0.26 -1.37 Decrease 9 Decrease 9 NO YES YES 2LZM L99I 0.00 51.00 3.00 1.40 -0.23 Decrease 9 Decrease 9 NO YES YES 2LZM L99I 0.00 64.00 5.70 1.50 -0.23 Decrease 9 Decrease 9 NO YES YES 2RN2 D134V 37.50 50.00 3.00 -0.31 -0.43 Increase 7 Increase 4 YES YES YES 2RN2 D134V 37.50 53.00 5.50 -1.12 -0.43 Increase 7 Increase 9 YES YES YES 1ROP D30V 96.50 69.00 7.00 0.40 -0.09 Decrease 0 Increase 1 NO NO YES 2RN2 E119V 36.10 50.00 3.00 -0.09 -1.94 Increase 0 Decrease 1 YES NO YES 2RN2 E119V 36.10 52.00 5.50 -0.74 -1.94 Increase 0 Decrease 1 YES NO YES 1VQB K24V 73.40 25.00 7.00 -0.80 -0.02 Increase 1 Decrease 0 YES NO YES 1IOB K97V 41.30 25.00 6.50 -0.80 -3.37 Decrease 2 Decrease 3 YES NO NO 2LZM C54V 3.60 70.00 6.50 0.70 -1.61 Decrease 1 Increase 5 NO NO YES 1VQB C33V 0.00 25.00 7.00 0.20 -1.68 Decrease 7 Decrease 9 NO YES YES 1BNI T105V 59.10 25.00 6.30 2.20 0.81 Decrease 3 Decrease 3 YES YES YES 1BNI T99V 0.70 25.00 6.30 2.70 0.64 Decrease 5 Decrease 4 YES YES YES 1BNI T26V 23.10 25.00 6.30 2.31 1.03 Decrease 3 Decrease 1 YES YES YES 1BNI T79V 80.00 25.00 6.30 -0.30 0.09 Decrease 0 Decrease 3 NO NO NO 2LZM T59V 46.90 41.00 2.00 2.80 -0.02 Decrease 3 Decrease 3 NO YES YES 2LZM T59V 46.90 63.00 6.50 1.50 -0.02 Decrease 2 Decrease 2 NO YES YES 1VQB T48V 25.20 25.00 7.00 -0.00 -0.67 Decrease 4 Decrease 5 NO NO NO 2LZM T157V 35.30 38.00 2.00 1.70 0.92 Decrease 3 Decrease 1 YES YES YES 2LZM T157V 35.30 42.00 2.00 1.60 0.92 Decrease 2 Decrease 3 YES YES YES 2LZM T157V 35.30 42.00 2.00 1.60 0.92 Decrease 2 Decrease 3 YES YES YES 2LZM T157V 35.30 53.00 3.00 1.20 0.92 Decrease 2 Decrease 1 YES YES YES 2LZM T152V 0.00 59.00 5.40 -0.20 -1.24 Decrease 2 Decrease 2 YES NO NO 2CI2 T22V 41.10 25.00 6.30 0.32 0.05 Decrease 3 Decrease 3 YES YES YES 2CI2 T55V 41.80 25.00 6.20 0.76 -0.44 Decrease 3 Decrease 3 NO YES YES 1VQB T62V 14.40 25.00 7.00 -1.30 1.05 Decrease 3 Decrease 0 NO NO NO 2LZM S44V 59.70 51.00 3.00 -0.10 0.22 Increase 7 Increase 9 NO YES YES 4LYZ S91V 0.00 74.00 6.40 0.08 -1.39 Decrease 2 Decrease 3 NO YES YES 2LZM S117V 1.70 66.00 5.40 -2.00 -2.26 Increase 2 Decrease 1 YES NO YES 2RN2 S68V 1.70 49.00 3.00 -0.60 -2.60 Decrease 2 Decrease 1 YES NO NO 2LZM A41V 29.00 41.00 2.00 -0.42 -0.09 Increase 1 Decrease 0 YES NO YES 2LZM A41V 29.00 51.00 2.80 -0.45 -0.09 Increase 4 Increase 2 YES YES YES 2LZM A41V 29.00 53.00 3.00 -0.41 -0.09 Increase 5 Increase 4 YES YES YES 2LZM A41V 29.00 66.00 5.40 -0.30 -0.09 Increase 7 Increase 9 YES YES YES 1STN A60V 52.60 20.00 7.00 2.90 0.32 Increase 1 Increase 2 YES NO NO 2RN2 A24V 0.00 50.00 3.00 -0.73 -2.57 Increase 3 Increase 1 YES YES YES 2RN2 A24V 0.00 52.00 5.50 -0.88 -2.57 Increase 3 Increase 4 YES YES YES 1BNI A32V 78.90 25.00 6.30 0.90 0.18 Decrease 0 Decrease 1 YES YES YES 1RN1 A21V 51.70 0.00 2.50 0.66 0.13 Decrease 4 Decrease 7 YES YES YES 1VQB A86V 90.70 25.00 7.00 -0.50 -0.75 Decrease 2 Decrease 2 YES NO NO 2LZM A129V 0.00 41.00 2.00 0.80 -2.19 Decrease 4 Decrease 4 NO YES YES 2LZM A129V 0.00 52.00 2.80 0.70 -2.19 Decrease 1 Increase 0 NO NO YES 4LYZ A31V 0.00 74.00 6.40 -1.20 -1.75 Increase 8 Increase 9 YES YES YES 2RN2 A52V 0.00 53.00 3.20 -1.70 -1.73 Decrease 1 Decrease 3 YES NO NO 2RN2 A52V 0.00 53.00 3.20 -1.70 -1.73 Decrease 1 Decrease 3 YES NO NO 2LZM A98V 0.00 40.00 3.00 4.90 -1.84 Decrease 6 Decrease 5 NO YES YES 4LYZ G102V 80.10 74.00 6.40 0.04 0.13 Increase 7 Increase 9 YES NO NO 1BNI G53V 21.60 54.00 6.30 7.80 -1.16 Decrease 1 Decrease 0 NO YES YES 1BNI G52V 2.50 54.00 6.30 8.40 -2.54 Decrease 3 Decrease 2 NO YES YES 1STN G88V 0.00 47.00 5.00 -0.60 -3.58 Decrease 4 Decrease 3 YES NO NO 1STN G88V 0.00 51.00 7.00 -0.50 -3.58 Decrease 3 Decrease 3 YES NO NO 1ANK G85V 8.90 51.00 7.20 2.40 2.76 Decrease 2 Decrease 1 YES YES YES 5CRO Y26V 80.50 45.00 7.00 -0.90 0.15 Increase 6 Increase 1 NO YES YES 1VQB F68V 36.40 25.00 7.00 5.00 0.47 Decrease 5 Decrease 6 YES YES YES 2LZM F153V 0.50 64.00 5.70 1.80 2.46 Decrease 5 Decrease 4 YES YES YES 2LZM F153V 0.50 64.00 5.70 1.80 2.46 Decrease 5 Decrease 4 YES YES YES 2CI2 F69V 17.40 25.00 6.20 2.39 1.35 Decrease 8 Decrease 7 YES YES YES 1VQB M77V 43.50 25.00 7.00 -1.20 -0.14 Decrease 2 Decrease 4 YES NO NO 3SSI M73V 94.00 53.00 3.20 0.46 0.23 Decrease 2 Decrease 4 YES YES YES 3SSI M73V 94.00 53.00 7.00 0.66 0.23 Decrease 2 Decrease 2 YES YES YES 3SSI M73V 94.00 53.00 9.50 0.95 0.23 Decrease 2 Decrease 1 YES YES YES 3SSI M103V 0.00 53.00 3.20 1.35 0.07 Decrease 4 Decrease 4 YES YES YES 3SSI M103V 0.00 80.00 9.50 2.22 0.07 Decrease 3 Decrease 4 YES YES YES 3SSI M103V 0.00 82.00 7.00 1.84 0.07 Decrease 3 Decrease 2 YES YES YES 1BNI I55V 46.50 25.00 6.30 0.30 0.51 Decrease 4 Decrease 2 YES YES YES 1BVC I142V 1.10 76.00 11.00 0.10 1.06 Increase 1 Increase 5 YES NO NO 1BNI I25V 8.60 25.00 6.30 1.10 0.87 Decrease 7 Decrease 6 YES YES YES 1BNI I109V 23.20 25.00 6.30 0.80 0.83 Decrease 9 Decrease 9 YES YES YES 1BNI I76V 0.00 25.00 6.30 0.80 0.85 Decrease 9 Decrease 9 YES YES YES 1BNI I96V 0.00 25.00 4.40 1.18 1.19 Decrease 9 Decrease 9 YES YES YES 1BNI I96V 0.00 25.00 6.30 0.90 1.19 Decrease 9 Decrease 8 YES YES YES 1BNI I96V 0.00 25.00 6.30 0.90 1.19 Decrease 9 Decrease 8 YES YES YES 1BNI I88V 0.00 25.00 4.40 1.47 0.96 Decrease 9 Decrease 9 YES YES YES 1BNI I88V 0.00 25.00 6.30 1.30 0.96 Decrease 9 Decrease 9 YES YES YES 1BNI I88V 0.00 48.00 6.30 1.10 0.96 Decrease 9 Decrease 9 YES YES YES 1BNI I4V 30.30 25.00 6.30 0.60 0.48 Decrease 9 Decrease 9 YES YES YES 1LZ1 I89V 3.80 49.00 2.70 0.35 1.26 Decrease 8 Decrease 8 YES YES YES 1LZ1 I89V 3.80 64.00 2.70 0.48 1.26 Decrease 7 Decrease 7 YES YES YES 1LZ1 I56V 1.60 49.00 2.70 1.34 1.36 Decrease 6 Decrease 9 YES YES YES 1LZ1 I56V 1.60 64.00 2.70 1.20 1.36 Decrease 4 Decrease 4 YES YES YES 1LZ1 I106V 2.70 64.00 2.70 0.72 1.53 Decrease 5 Decrease 1 YES YES YES 1LZ1 I106V 2.70 49.00 2.70 0.98 1.53 Decrease 7 Decrease 7 YES YES YES 1LZ1 I23V 8.10 49.00 2.70 0.41 1.20 Decrease 7 Decrease 3 YES YES YES 1LZ1 I23V 8.10 64.00 2.70 0.36 1.20 Decrease 3 Increase 2 YES NO YES 1BNI I51V 0.00 25.00 4.40 1.86 1.37 Decrease 9 Decrease 9 YES YES YES 1BNI I51V 0.00 25.00 6.30 1.80 1.37 Decrease 9 Decrease 9 YES YES YES 1LZ1 I59V 1.60 49.00 2.70 0.93 1.25 Decrease 9 Decrease 9 YES YES YES 1LZ1 I59V 1.60 64.00 2.70 1.10 1.25 Decrease 8 Decrease 9 YES YES YES 4LYZ I55V 2.20 74.00 6.40 0.91 1.08 Decrease 3 Increase 1 YES NO YES 1VQB I78V 50.80 25.00 7.00 1.30 0.11 Decrease 7 Decrease 6 YES YES YES 1VQB I6V 0.50 25.00 7.00 0.70 1.00 Decrease 9 Decrease 9 YES YES YES 2CI2 I49V 38.40 25.00 6.30 -0.08 0.08 Decrease 6 Decrease 6 NO NO NO 2CI2 I49V 38.40 25.00 6.30 -0.08 0.08 Decrease 6 Decrease 6 NO NO NO 2LZM I3V 11.90 41.00 2.00 0.60 1.33 Decrease 7 Decrease 6 YES YES YES 2LZM I3V 11.90 64.00 6.50 0.40 1.33 Decrease 6 Decrease 6 YES YES YES 2CI2 I48V 21.60 25.00 3.50 0.92 0.96 Decrease 7 Decrease 7 YES YES YES 2CI2 I48V 21.60 25.00 6.30 1.09 0.96 Decrease 7 Decrease 5 YES YES YES 2CI2 I48V 21.60 46.00 6.30 1.11 0.96 Decrease 6 Decrease 5 YES YES YES 1VQB I47V 2.20 25.00 7.00 2.60 1.00 Decrease 9 Decrease 9 YES YES YES 1BVC I28V 2.70 76.00 11.00 -0.00 1.05 Decrease 2 Decrease 3 NO NO NO 2CI2 I39V 0.00 25.00 3.00 1.20 1.23 Decrease 6 Decrease 4 YES YES YES 2CI2 I39V 0.00 25.00 3.50 1.16 1.23 Decrease 6 Decrease 5 YES YES YES 2CI2 I39V 0.00 25.00 6.20 1.30 1.23 Decrease 6 Decrease 4 YES YES YES 2CI2 I39V 0.00 25.00 6.30 1.27 1.23 Decrease 6 Decrease 6 YES YES YES 2CI2 I39V 0.00 25.00 6.20 1.30 1.23 Decrease 6 Decrease 4 YES YES YES 2CI2 I76V 1.10 25.00 3.00 -0.09 1.17 Decrease 7 Decrease 9 NO NO NO 2CI2 I76V 1.10 25.00 6.30 -0.21 1.17 Decrease 7 Decrease 7 NO NO NO 2CI2 I76V 1.10 46.00 6.30 -0.19 1.17 Decrease 6 Decrease 7 NO NO NO 1VQB L49V 3.30 25.00 7.00 2.90 1.75 Decrease 9 Decrease 9 YES YES YES 1ROP L41V 45.30 25.00 6.00 2.53 0.01 Decrease 9 Decrease 9 YES YES YES 1VQB L28V 28.40 25.00 7.00 -1.10 -0.60 Decrease 9 Decrease 9 YES NO NO 1BNI L89V 0.00 25.00 6.30 0.30 1.34 Decrease 9 Decrease 9 YES YES YES 1BVC L135V 0.50 76.00 11.00 2.20 1.18 Decrease 7 Decrease 7 YES YES YES 1BVC L29V 1.60 76.00 11.00 1.70 1.21 Decrease 9 Decrease 9 YES YES YES 1VQB L37V 60.10 25.00 7.00 3.50 0.54 Decrease 9 Decrease 9 YES YES YES 1BVC L69V 2.20 76.00 11.00 0.10 1.32 Decrease 9 Decrease 9 YES YES YES 2CI2 L51V 20.80 25.00 6.20 0.50 -0.51 Decrease 9 Decrease 9 NO YES YES 2CI2 L51V 20.80 25.00 6.20 0.50 -0.51 Decrease 9 Decrease 9 NO YES YES 1VQB L81V 14.70 25.00 7.00 0.20 0.65 Decrease 9 Decrease 9 YES YES YES 2LZM L99V 0.00 51.00 3.00 2.30 0.88 Decrease 9 Decrease 9 YES YES YES 2LZM L99V 0.00 64.00 5.70 2.00 0.88 Decrease 9 Decrease 9 YES YES YES 2LZM V131D 59.20 53.00 3.00 -0.08 -0.07 Increase 1 Increase 4 YES YES YES 2LZM V131E 59.20 53.00 3.00 -0.20 -0.26 Increase 1 Increase 1 YES YES YES 1CYO V61E 75.50 25.00 7.00 1.05 0.68 Decrease 3 Decrease 5 YES YES YES 1CYO V61K 75.50 25.00 7.00 2.39 0.34 Decrease 7 Decrease 6 YES YES YES 1DDR V75R 5.90 15.00 7.80 2.80 3.18 Decrease 9 Decrease 9 YES YES YES 1CYO V61H 75.50 25.00 7.00 1.60 0.47 Decrease 6 Decrease 8 YES YES YES 1CYO V45H 46.20 25.00 7.00 1.65 0.82 Decrease 8 Decrease 8 YES YES YES 1DDR V75H 5.90 15.00 6.50 1.90 1.56 Decrease 9 Decrease 9 YES YES YES 1DDR V75H 5.90 15.00 7.80 1.70 1.56 Decrease 9 Decrease 9 YES YES YES 1VQB V19C 64.40 25.00 7.00 0.30 0.74 Decrease 6 Decrease 2 YES YES YES 1VQB V70C 63.10 25.00 7.00 3.10 0.20 Decrease 7 Decrease 6 YES YES YES 1VQB V43C 33.20 25.00 7.00 2.10 0.87 Decrease 9 Decrease 9 YES YES YES 2LZM V149C 0.00 40.00 3.00 2.20 2.15 Decrease 8 Decrease 8 YES YES YES 2LZM V149C 0.00 59.00 5.40 2.00 2.15 Decrease 7 Decrease 8 YES YES YES 1DDR V75C 5.90 15.00 7.80 0.20 2.30 Decrease 9 Decrease 9 YES YES YES 1VQB V63C 15.00 25.00 7.00 4.10 1.41 Decrease 9 Decrease 9 YES YES YES 1VQB V45C 28.60 25.00 7.00 0.10 1.09 Decrease 9 Decrease 9 YES YES YES 1VQB V35C 6.50 25.00 7.00 1.40 1.72 Decrease 9 Decrease 9 YES YES YES 1VQB V19T 64.40 25.00 7.00 0.60 0.64 Decrease 8 Decrease 8 YES YES YES 2LZM V131T 59.20 41.00 2.00 0.11 0.31 Decrease 5 Decrease 8 YES YES YES 2LZM V131T 59.20 51.00 2.80 0.05 0.31 Decrease 3 Increase 0 YES NO YES 2LZM V131T 59.20 53.00 3.00 0.12 0.31 Decrease 3 Increase 1 YES NO YES 1VQB V70T 63.10 25.00 7.00 3.50 0.26 Decrease 8 Decrease 8 YES YES YES 1BNI V36T 42.30 25.00 6.30 1.10 0.25 Decrease 8 Decrease 8 YES YES YES 1BNI V45T 26.70 25.00 6.30 2.40 2.37 Decrease 8 Decrease 9 YES YES YES 1BNI V10T 0.00 25.00 6.30 2.50 1.03 Decrease 9 Decrease 9 YES YES YES 1CYO V45T 46.20 25.00 7.00 0.96 0.39 Decrease 7 Decrease 7 YES YES YES 2LZM V87T 1.30 51.00 3.00 1.60 2.00 Decrease 8 Decrease 9 YES YES YES 2CI2 V82T 13.00 25.00 6.30 1.15 0.70 Decrease 9 Decrease 9 YES YES YES 2LZM V75T 22.10 51.00 3.00 1.30 1.25 Decrease 9 Decrease 9 YES YES YES 2CI2 V53T 47.50 25.00 6.30 1.03 1.21 Decrease 9 Decrease 9 YES YES YES 2CI2 V53T 47.50 25.00 6.30 1.03 1.21 Decrease 9 Decrease 9 YES YES YES 1VQB V43T 33.20 25.00 7.00 1.60 0.36 Decrease 9 Decrease 9 YES YES YES 2LZM V149T 0.00 51.00 3.00 2.80 2.23 Decrease 8 Decrease 7 YES YES YES 2LZM V149T 0.00 59.00 5.40 3.00 2.23 Decrease 8 Decrease 8 YES YES YES 1BVC V68T 22.80 4.00 7.80 0.60 1.10 Decrease 9 Decrease 9 YES YES YES 1C9O V64T 33.20 70.00 7.00 0.26 0.80 Decrease 8 Decrease 7 YES YES YES 1VQB V63T 15.00 25.00 7.00 5.00 1.61 Decrease 9 Decrease 9 YES YES YES 1VQB V45T 28.60 25.00 7.00 3.50 1.04 Decrease 9 Decrease 9 YES YES YES 1VQB V35T 6.50 25.00 7.00 5.30 1.89 Decrease 9 Decrease 9 YES YES YES 2CI2 V79T 24.10 25.00 6.30 0.38 0.94 Decrease 9 Decrease 9 YES YES YES 2LZM V131S 59.20 53.00 3.00 0.05 -0.22 Decrease 3 Decrease 1 NO YES YES 2LZM V149S 0.00 59.00 5.40 4.40 2.78 Decrease 9 Decrease 8 YES YES YES 1DDR V75S 5.90 15.00 7.80 1.90 0.88 Decrease 9 Decrease 9 YES YES YES 1LZ1 V110P 51.40 68.00 2.80 -0.50 -1.61 Increase 9 Increase 9 YES YES YES 1VQB V70P 63.10 25.00 7.00 5.00 -1.14 Decrease 4 Decrease 1 NO YES YES 1BPI V34A 41.00 39.00 7.00 1.20 1.19 Decrease 9 Decrease 9 YES YES YES 1LZ1 V74A 58.60 64.00 2.70 0.36 0.51 Decrease 5 Decrease 5 YES YES YES 1LZ1 V74A 58.60 49.00 2.70 0.43 0.51 Decrease 8 Decrease 7 YES YES YES 1LZ1 V110A 51.40 64.00 2.70 -0.53 -0.29 Increase 4 Increase 5 YES YES YES 1LZ1 V110A 51.40 49.00 2.70 -0.07 -0.29 Decrease 1 Decrease 4 YES NO NO 1LZ1 V2A 64.40 64.00 2.70 1.51 0.98 Decrease 1 Increase 3 YES NO YES 1LZ1 V2A 64.40 64.00 2.70 1.51 0.98 Decrease 1 Increase 3 YES NO YES 2LZM V131A 59.20 40.00 2.00 -0.27 -0.59 Decrease 2 Decrease 4 YES NO NO 2LZM V131A 59.20 41.00 2.00 -0.15 -0.59 Decrease 1 Decrease 4 YES NO NO 2LZM V131A 59.20 51.00 2.80 -0.30 -0.59 Increase 3 Increase 4 YES YES YES 2LZM V131A 59.20 53.00 3.00 -0.33 -0.59 Increase 4 Increase 0 YES YES YES 2LZM V131A 59.20 66.00 5.40 -0.39 -0.59 Increase 8 Increase 8 YES YES YES 2RN2 V74A 0.70 49.00 3.00 2.20 1.59 Decrease 4 Decrease 1 YES YES YES 2RN2 V74A 0.70 52.00 5.50 3.40 1.59 Decrease 2 Decrease 7 YES YES YES 1DDR V88A 26.00 20.00 7.20 -0.20 1.32 Decrease 9 Decrease 9 NO NO NO 1BNI V36A 42.30 25.00 6.30 1.30 1.08 Decrease 9 Decrease 9 YES YES YES 1LZ1 V121A 8.50 64.00 2.70 1.44 1.13 Decrease 9 Decrease 9 YES YES YES 1LZ1 V121A 8.50 49.00 2.70 1.75 1.13 Decrease 9 Decrease 9 YES YES YES 1BNI V45A 26.70 25.00 6.30 1.80 1.89 Decrease 9 Decrease 9 YES YES YES 2CI2 V57A 37.70 25.00 6.20 1.47 0.38 Decrease 9 Decrease 9 YES YES YES 2LZM V94A 18.90 51.00 3.00 1.80 0.96 Decrease 8 Decrease 8 YES YES YES 2ABD V77A 4.60 5.00 5.30 1.14 1.91 Decrease 9 Decrease 9 YES YES YES 1LZ1 V130A 54.70 49.00 2.70 1.12 1.52 Decrease 9 Decrease 9 YES YES YES 1LZ1 V130A 54.70 64.00 2.70 0.84 1.52 Decrease 8 Decrease 9 YES YES YES 1PGA V54A 0.00 25.00 7.00 0.10 2.72 Decrease 8 Decrease 7 YES YES YES 2ABD V12A 7.20 5.00 5.30 1.69 1.33 Decrease 9 Decrease 9 YES YES YES 1BNI V10A 0.00 25.00 6.30 3.40 1.63 Decrease 9 Decrease 9 YES YES YES 2LZM V87A 1.30 51.00 3.00 1.70 1.42 Decrease 9 Decrease 9 YES YES YES 1LZ1 V100A 0.70 49.00 2.70 0.57 2.06 Decrease 8 Decrease 9 YES YES YES 1LZ1 V100A 0.70 64.00 2.70 0.26 2.06 Decrease 8 Decrease 8 YES YES YES 2CI2 V82A 13.00 25.00 6.30 1.45 1.15 Decrease 9 Decrease 9 YES YES YES 1LZ1 V99A 2.00 64.00 2.70 0.98 1.93 Decrease 9 Decrease 9 YES YES YES 1LZ1 V99A 2.00 49.00 2.70 0.89 1.93 Decrease 9 Decrease 9 YES YES YES 1LZ1 V125A 16.90 64.00 2.70 1.32 1.59 Decrease 9 Decrease 9 YES YES YES 1LZ1 V125A 16.90 49.00 2.70 1.60 1.59 Decrease 9 Decrease 9 YES YES YES 2CI2 V38A 32.50 25.00 6.30 0.46 0.52 Decrease 9 Decrease 9 YES YES YES 2CI2 V38A 32.50 25.00 6.20 0.49 0.52 Decrease 9 Decrease 9 YES YES YES 2CI2 V38A 32.50 25.00 6.30 0.46 0.52 Decrease 9 Decrease 9 YES YES YES 2CI2 V38A 32.50 46.00 6.30 0.48 0.52 Decrease 8 Decrease 9 YES YES YES 1MBG V103A 0.00 25.00 7.50 2.32 1.98 Decrease 8 Decrease 8 YES YES YES 2LZM V71A 3.90 51.00 3.00 1.50 1.81 Decrease 9 Decrease 9 YES YES YES 1LZ1 V93A 3.30 49.00 2.70 1.00 1.48 Decrease 9 Decrease 9 YES YES YES 1LZ1 V93A 3.30 64.00 2.70 0.74 1.48 Decrease 9 Decrease 9 YES YES YES 2CI2 V53A 47.50 25.00 6.30 0.64 0.27 Decrease 9 Decrease 9 YES YES YES 2CI2 V53A 47.50 46.00 6.30 0.63 0.27 Decrease 9 Decrease 9 YES YES YES 1BVC V66A 31.20 82.00 9.60 -0.80 0.38 Increase 2 Increase 0 NO YES YES 1BVC V13A 2.00 82.00 9.60 0.70 1.65 Increase 3 Increase 6 YES NO NO 1BVC V114A 3.90 82.00 9.60 1.40 1.50 Decrease 7 Decrease 5 YES YES YES 2LZM V111A 0.00 51.00 3.00 1.30 1.82 Decrease 9 Decrease 9 YES YES YES 2LZM V149A 0.00 51.00 3.00 3.20 1.77 Decrease 9 Decrease 9 YES YES YES 2LZM V149A 0.00 59.00 5.40 3.10 1.77 Decrease 9 Decrease 9 YES YES YES 1DDR V75A 5.90 15.00 7.80 0.20 2.26 Decrease 9 Decrease 9 YES YES YES 2CI2 V70A 7.80 25.00 3.00 2.17 2.49 Decrease 9 Decrease 9 YES YES YES 2CI2 V70A 7.80 25.00 6.30 1.95 2.49 Decrease 9 Decrease 9 YES YES YES 2CI2 V70A 7.80 25.00 6.30 1.95 2.49 Decrease 9 Decrease 9 YES YES YES 2CI2 V66A 0.00 25.00 3.50 4.91 2.82 Decrease 9 Decrease 9 YES YES YES 2CI2 V66A 0.00 25.00 6.30 4.88 2.82 Decrease 9 Decrease 9 YES YES YES 2LZM V103A 5.20 51.00 3.00 2.20 1.68 Decrease 9 Decrease 9 YES YES YES 1VQB V45A 28.60 25.00 7.00 2.10 1.20 Decrease 9 Decrease 9 YES YES YES 1VQB V35A 6.50 25.00 7.00 2.20 2.24 Decrease 9 Decrease 9 YES YES YES 2CI2 V79A 24.10 25.00 6.30 1.51 1.26 Decrease 9 Decrease 9 YES YES YES 3SSI V13A 41.00 82.00 7.00 6.78 0.84 Decrease 8 Decrease 8 YES YES YES 3SSI V13A 41.00 82.00 9.50 6.93 0.84 Decrease 7 Decrease 7 YES YES YES 2LZM V131G 59.20 53.00 3.00 0.68 0.55 Decrease 6 Decrease 4 YES YES YES 1CYO V45G 46.20 25.00 7.00 1.91 0.86 Decrease 9 Decrease 9 YES YES YES 2CI2 V82G 13.00 25.00 6.30 3.50 1.91 Decrease 9 Decrease 9 YES YES YES 3MBP V8G 21.50 25.00 7.60 1.10 2.21 Decrease 9 Decrease 9 YES YES YES 2CI2 V53G 47.50 25.00 6.30 2.43 0.94 Decrease 9 Decrease 9 YES YES YES 2LZM V149G 0.00 59.00 5.40 4.90 3.76 Decrease 9 Decrease 8 YES YES YES 2CI2 V79G 24.10 25.00 6.30 3.24 1.96 Decrease 9 Decrease 9 YES YES YES 3SSI V13G 41.00 82.00 9.50 9.31 1.60 Decrease 9 Decrease 9 YES YES YES 1CYO V61Y 75.50 25.00 7.00 1.34 0.39 Decrease 0 Increase 2 YES NO YES 1DDR V75Y 5.90 15.00 7.80 2.30 -0.78 Decrease 9 Decrease 9 NO YES YES 2LZM V111F 0.00 51.00 3.00 1.43 -2.94 Decrease 8 Decrease 8 NO YES YES 2LZM V111F 0.00 64.00 5.70 1.69 -2.94 Decrease 7 Decrease 6 NO YES YES 1STN V23F 0.70 40.00 5.30 1.50 -3.27 Decrease 9 Decrease 9 NO YES YES 1VQB V35F 6.50 25.00 7.00 3.20 -2.88 Decrease 9 Decrease 9 NO YES YES 3SSI V13F 41.00 82.00 7.00 5.69 -0.38 Decrease 6 Decrease 6 NO YES YES 3SSI V13F 41.00 82.00 9.50 5.33 -0.38 Decrease 6 Decrease 4 NO YES YES 2LZM V131M 59.20 53.00 3.00 -0.12 -0.30 Increase 1 Decrease 0 YES NO YES 2LZM V103M 5.20 65.00 5.40 1.20 -0.50 Decrease 9 Decrease 8 NO YES YES 1VQB V35M 6.50 25.00 7.00 1.10 0.51 Decrease 9 Decrease 9 YES YES YES 3SSI V13M 41.00 82.00 7.00 5.92 0.24 Decrease 8 Decrease 6 YES YES YES 3SSI V13M 41.00 82.00 9.50 5.43 0.24 Decrease 8 Decrease 9 YES YES YES 2LZM V131I 59.20 53.00 3.00 -0.16 -0.16 Increase 9 Increase 9 YES YES YES 2RN2 V74I 0.70 49.00 3.00 -0.70 -0.85 Increase 6 Increase 6 YES YES YES 2RN2 V74I 0.70 52.00 5.50 -0.60 -0.85 Increase 7 Increase 8 YES YES YES 1DDR V88I 26.00 20.00 7.20 1.73 -0.53 Decrease 8 Decrease 7 NO YES YES 2AKY V8I 0.70 25.00 7.50 1.20 -1.17 Decrease 8 Decrease 8 NO YES YES 1MBG V103I 0.00 25.00 7.50 -0.69 -1.06 Increase 0 Decrease 5 YES NO YES 2LZM V111I 0.00 51.00 3.00 0.69 -1.13 Decrease 7 Decrease 6 NO YES YES 2LZM V111I 0.00 64.00 5.70 0.85 -1.13 Decrease 2 Decrease 0 NO YES YES 2LZM V149I 0.00 59.00 5.40 0.10 -1.19 Decrease 2 Decrease 0 NO YES YES 1DDR V75I 5.90 15.00 7.80 2.00 -0.84 Decrease 9 Decrease 9 NO YES YES 1VQB V35I 6.50 25.00 7.00 0.70 -0.77 Decrease 9 Decrease 9 NO YES YES 3SSI V13I 41.00 82.00 7.00 0.84 -0.36 Decrease 5 Decrease 4 NO YES YES 3SSI V13I 41.00 82.00 9.50 0.94 -0.36 Decrease 5 Decrease 4 NO YES YES 2LZM V131L 59.20 53.00 3.00 -0.09 -0.48 Increase 10 Increase 9 YES YES YES 2RN2 V74L 0.70 50.00 3.00 -1.10 -1.04 Increase 10 Increase 10 YES YES YES 2RN2 V74L 0.70 50.00 3.00 -1.10 -1.04 Increase 10 Increase 10 YES YES YES 2RN2 V74L 0.70 52.00 5.50 -0.90 -1.04 Increase 10 Increase 10 YES YES YES 1MBG V103L 0.00 25.00 7.50 -2.44 -0.98 Increase 8 Decrease 1 YES NO YES 1STN V66L 2.60 47.00 5.00 -0.60 -1.09 Increase 5 Increase 1 YES YES YES 1STN V66L 2.60 51.00 7.00 -0.80 -1.09 Increase 7 Increase 7 YES YES YES 1VQB V45L 28.60 25.00 7.00 3.00 -1.00 Decrease 5 Decrease 6 NO YES YES 1VQB V35L 6.50 25.00 7.00 2.70 -0.75 Decrease 8 Decrease 8 NO YES YES 3SSI V13L 41.00 82.00 7.00 2.21 -0.54 Decrease 2 Decrease 4 NO YES YES 3SSI V13L 41.00 82.00 9.50 2.52 -0.54 Decrease 2 Decrease 1 NO YES YES